Last reviewed · How we verify
Lignocaine
At a glance
| Generic name | Lignocaine |
|---|---|
| Also known as | Intravenous lignocaine, xylocaine, 2% lignocaine 1 ml, Lidocaine, Lignocaine infusion |
| Sponsor | University of Malaya |
| Target | 5-hydroxytryptamine receptor 3A, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, Sodium channel protein type 10 subunit alpha |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Approved indications
- Hemorrhoids
- Infestation by Phthirus pubis
- Infestation by Sarcoptes scabiei var hominis
- Itching of skin
- Local Anesthesia for Endotracheal Intubation
- Local Anesthesia for Ophthalmologic Procedure
- Local Anesthesia for Urethral Pain
- Local anesthesia
- Local anesthetic intrathecal block
- Minor Skin Wound Pain
- Mouth Irritation
- Neuralgia
- Pediculosis capitis
- Postherpetic neuralgia
- Premature ejaculation
- Prevent Minor Bacterial Skin Infection
- Pruritus ani
- Regional Anesthesia for Ophthalmologic Surgery
- Skin irritation
- Suppression of the Gag Reflex
Common side effects
Key clinical trials
- Effect of Lidocaine Infusion Versus Dexmedemidine Infusion on the Neurocognitive Function of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography(ERCP): a Randomized, Controlled Trial. (NA)
- The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
- Closed Versus Open Lateral Internal Sphincterotomy for Chronic Anal Fissure (NA)
- OMT for Adhesive Capsulitis (PHASE4)
- Sphenopalatine Ganglion Block for Post-Dural Puncture Headache: A Pilot Randomised Controlled Trial (NA)
- The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster (NA)
- Effects of Different Drugs for Glottic Atomization on Postoperative Sore Throat After Thyroid Surgery (PHASE4)
- Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |