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Probenecid 500 Milligrams (mg) — Competitive Intelligence Brief
phase 3
Uricosuric agent
URAT1 (urate transporter 1)
Rheumatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Probenecid 500 Milligrams (mg) (Probenecid 500 Milligrams (mg)) — University of Miami. Probenecid inhibits the renal tubular reabsorption of uric acid, increasing urinary excretion and lowering serum uric acid levels.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Probenecid 500 Milligrams (mg) TARGET | Probenecid 500 Milligrams (mg) | University of Miami | phase 3 | Uricosuric agent | URAT1 (urate transporter 1) | |
| phenytoin and probenecid | phenytoin and probenecid | Jim McAuley | marketed | Anticonvulsant and uricosuric agent combination | Voltage-gated sodium channels (phenytoin); organic acid transporter (probenecid) | |
| ULO | ULO | Merck Sharp & Dohme LLC | marketed | Uricosuric agent; URAT1 inhibitor | URAT1 (urate transporter 1) | |
| Benzbromarone (drug) | Benzbromarone (drug) | Tottori University Hospital | marketed | Uricosuric agent | URAT1 (urate transporter 1) | |
| olmesartan medoxomil+probenecid | olmesartan medoxomil+probenecid | Central South University | marketed | Angiotensin II receptor blocker + uricosuric agent | AT1 receptor (angiotensin II type 1 receptor); uric acid transporter (URAT1) | |
| Uritos® | Uritos® | R-Pharm | phase 3 | Uricosuric agent / URAT1 inhibitor | URAT1 (urate transporter 1) | |
| Bempedoic Acid Tablet | Bempedoic Acid Tablet | Gan & Lee Pharmaceuticals. | phase 3 | Uricosuric agent / Xanthine oxidase inhibitor | AMPK (AMP-activated protein kinase) / Xanthine oxidase pathway |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Uricosuric agent class)
- Tottori University Hospital · 1 drug in this class
- University of Miami · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Probenecid 500 Milligrams (mg) — Competitive Intelligence Brief. https://druglandscape.com/ci/probenecid-500-milligrams-mg. Accessed 2026-06-10.
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