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Pregabalin & Magnesium sulphate — Competitive Intelligence Brief
phase 3
Anticonvulsant/analgesic combination
Alpha-2-delta calcium channel subunit; NMDA receptor
Oncology; Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Pregabalin & Magnesium sulphate (Pregabalin & Magnesium sulphate) — National Cancer Institute, Egypt. Pregabalin reduces neuronal calcium influx and neurotransmitter release while magnesium sulphate acts as an NMDA receptor antagonist, together modulating neuropathic pain and potentially chemotherapy-induced peripheral neuropathy.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pregabalin & Magnesium sulphate TARGET | Pregabalin & Magnesium sulphate | National Cancer Institute, Egypt | phase 3 | Anticonvulsant/analgesic combination | Alpha-2-delta calcium channel subunit; NMDA receptor | |
| Gabapentin/B-complex | Gabapentin/B-complex | Merck KGaA, Darmstadt, Germany | marketed | Anticonvulsant/analgesic combination with vitamin supplementation | Alpha-2-delta subunit of voltage-gated calcium channels (gabapentin component) | |
| Naltrexone plus Gabapentin | Naltrexone plus Gabapentin | Medical University of South Carolina | phase 3 | Opioid antagonist + anticonvulsant/analgesic combination | Opioid receptors (mu, delta, kappa) + voltage-gated calcium channels (Cav2.1, Cav2.2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anticonvulsant/analgesic combination class)
- National Cancer Institute, Egypt · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Pregabalin & Magnesium sulphate — Competitive Intelligence Brief. https://druglandscape.com/ci/pregabalin-magnesium-sulphate. Accessed 2026-05-18.
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