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Placebo matching with Saxagliptin — Competitive Intelligence Brief
phase 3
DPP-4 inhibitor
DPP-4
Diabetes
Small molecule
Live · refreshed every 30 min
Target snapshot
Placebo matching with Saxagliptin (Placebo matching with Saxagliptin) — AstraZeneca. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which increases the levels of incretin hormones, thereby enhancing glucose-dependent insulin secretion.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Placebo matching with Saxagliptin TARGET | Placebo matching with Saxagliptin | AstraZeneca | phase 3 | DPP-4 inhibitor | DPP-4 | |
| SGLT2 inhibitor and DPP-4 inhibitor | SGLT2 inhibitor and DPP-4 inhibitor | LMC Diabetes & Endocrinology Ltd. | marketed | SGLT2 inhibitor and DPP-4 inhibitor combination | SGLT2 (sodium-glucose cotransporter 2) and DPP-4 (dipeptidyl peptidase-4) | |
| Sitagliptin phosphate/metformin hydrochloride FDC | Sitagliptin phosphate/metformin hydrochloride FDC | Merck Sharp & Dohme LLC | marketed | DPP-4 inhibitor / biguanide combination | DPP-4 enzyme / metformin (AMPK pathway) | |
| CSII followed by Lina+MET | CSII followed by Lina+MET | Sun Yat-sen University | marketed | Insulin therapy combined with DPP-4 inhibitor and biguanide | Insulin receptor (CSII); DPP-4 enzyme (linagliptin); mitochondrial glycerophosphate dehydrogenase (metformin) | |
| Pioglitazone + Alogliptin | Pioglitazone + Alogliptin | Celltrion Pharm, Inc. | marketed | Thiazolidinedione + DPP-4 inhibitor combination | PPAR-γ and DPP-4 | |
| Janumet, Lantus | Janumet, Lantus | Chinese University of Hong Kong | marketed | DPP-4 inhibitor + biguanide (Janumet); long-acting basal insulin (Lantus) | DPP-4 enzyme, metformin (AMPK pathway), insulin receptor (Lantus) | |
| Sitagliptin - DPP4i | Sitagliptin - DPP4i | Royal Devon and Exeter NHS Foundation Trust | marketed | DPP-4 inhibitor | DPP-4 (dipeptidyl peptidase-4) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (DPP-4 inhibitor class)
- Merck Sharp & Dohme LLC · 5 drugs in this class
- Daewoong Pharmaceutical Co. LTD. · 4 drugs in this class
- AstraZeneca · 4 drugs in this class
- LG Life Sciences · 2 drugs in this class
- Tanabe Pharma Corporation · 2 drugs in this class
- Ain Shams University · 2 drugs in this class
- Ono Pharmaceutical Co. Ltd · 2 drugs in this class
- Cinnagen · 1 drug in this class
- GRADE Study Group · 1 drug in this class
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · 1 drug in this class
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- Placebo matching with Saxagliptin CI watch — RSS
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Cite this brief
Drug Landscape (2026). Placebo matching with Saxagliptin — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-matching-with-saxagliptin. Accessed 2026-05-16.
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