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PAx5/PCMx5 — Competitive Intelligence Brief

PAx5/PCMx5 (PAx5/PCMx5) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Multi-agent chemotherapy regimen. Area: Oncology.

phase 3 Multi-agent chemotherapy regimen Oncology Small molecule Live · refreshed every 30 min

Target snapshot

PAx5/PCMx5 (PAx5/PCMx5) — SWOG Cancer Research Network. PAx5/PCMx5 is a chemotherapy regimen combining prednisone, doxorubicin, cyclophosphamide, and other agents designed to treat hematologic malignancies.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
PAx5/PCMx5 TARGET PAx5/PCMx5 SWOG Cancer Research Network phase 3 Multi-agent chemotherapy regimen
Modified HIT-SKK Cycle B4-5 Modified HIT-SKK Cycle B4-5 Nationwide Children's Hospital phase 3 Multi-agent chemotherapy regimen
PACx14 PACx14 SWOG Cancer Research Network phase 3 Multi-agent chemotherapy regimen
Prednisone, Dexamethasone, Vincristine, Daunorubicin Prednisone, Dexamethasone, Vincristine, Daunorubicin St. Jude Children's Research Hospital phase 3 Multi-agent chemotherapy regimen
Etoposide, Thioguanine, Cyclophosphamide, Busulfan, Melphalan Etoposide, Thioguanine, Cyclophosphamide, Busulfan, Melphalan Dutch Childhood Oncology Group phase 3 Multi-agent chemotherapy regimen; alkylating agents, antimetabolite, topoisomerase II inhibitor
Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone St. Jude Children's Research Hospital phase 3 Multi-agent chemotherapy regimen
HDS vs ProMECE/CytaBOM HDS vs ProMECE/CytaBOM Gruppo Italiano Studio Linfomi phase 3 Multi-agent chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Multi-agent chemotherapy regimen class)

  1. St. Jude Children's Research Hospital · 3 drugs in this class
  2. Nationwide Children's Hospital · 2 drugs in this class
  3. SWOG Cancer Research Network · 2 drugs in this class
  4. Children's Cancer Group, China · 1 drug in this class
  5. Gruppo Italiano Studio Linfomi · 1 drug in this class
  6. Polish Adult Leukemia Group · 1 drug in this class

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Cite this brief

Drug Landscape (2026). PAx5/PCMx5 — Competitive Intelligence Brief. https://druglandscape.com/ci/pax5-pcmx5. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing