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PAx5/PCMx5 — Competitive Intelligence Brief
phase 3
Multi-agent chemotherapy regimen
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
PAx5/PCMx5 (PAx5/PCMx5) — SWOG Cancer Research Network. PAx5/PCMx5 is a chemotherapy regimen combining prednisone, doxorubicin, cyclophosphamide, and other agents designed to treat hematologic malignancies.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| PAx5/PCMx5 TARGET | PAx5/PCMx5 | SWOG Cancer Research Network | phase 3 | Multi-agent chemotherapy regimen | ||
| Modified HIT-SKK Cycle B4-5 | Modified HIT-SKK Cycle B4-5 | Nationwide Children's Hospital | phase 3 | Multi-agent chemotherapy regimen | ||
| PACx14 | PACx14 | SWOG Cancer Research Network | phase 3 | Multi-agent chemotherapy regimen | ||
| Prednisone, Dexamethasone, Vincristine, Daunorubicin | Prednisone, Dexamethasone, Vincristine, Daunorubicin | St. Jude Children's Research Hospital | phase 3 | Multi-agent chemotherapy regimen | ||
| Etoposide, Thioguanine, Cyclophosphamide, Busulfan, Melphalan | Etoposide, Thioguanine, Cyclophosphamide, Busulfan, Melphalan | Dutch Childhood Oncology Group | phase 3 | Multi-agent chemotherapy regimen; alkylating agents, antimetabolite, topoisomerase II inhibitor | ||
| Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone | Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone | St. Jude Children's Research Hospital | phase 3 | Multi-agent chemotherapy regimen | ||
| HDS vs ProMECE/CytaBOM | HDS vs ProMECE/CytaBOM | Gruppo Italiano Studio Linfomi | phase 3 | Multi-agent chemotherapy regimen |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Multi-agent chemotherapy regimen class)
- St. Jude Children's Research Hospital · 3 drugs in this class
- Nationwide Children's Hospital · 2 drugs in this class
- SWOG Cancer Research Network · 2 drugs in this class
- Children's Cancer Group, China · 1 drug in this class
- Gruppo Italiano Studio Linfomi · 1 drug in this class
- Polish Adult Leukemia Group · 1 drug in this class
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Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- PAx5/PCMx5 CI watch — RSS
- PAx5/PCMx5 CI watch — Atom
- PAx5/PCMx5 CI watch — JSON
- PAx5/PCMx5 alone — RSS
- Whole Multi-agent chemotherapy regimen class — RSS
Cite this brief
Drug Landscape (2026). PAx5/PCMx5 — Competitive Intelligence Brief. https://druglandscape.com/ci/pax5-pcmx5. Accessed 2026-06-10.
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