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OROS MPH — Competitive Intelligence Brief
marketed
Central nervous system stimulant; dopamine-norepinephrine reuptake inhibitor
Dopamine transporter (DAT); norepinephrine transporter (NET)
Psychiatry / Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
OROS MPH (OROS MPH) — Ortho-McNeil Janssen Scientific Affairs, LLC. OROS MPH is an extended-release formulation of methylphenidate that provides sustained dopamine and norepinephrine reuptake inhibition throughout the day.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| OROS MPH TARGET | OROS MPH | Ortho-McNeil Janssen Scientific Affairs, LLC | marketed | Central nervous system stimulant; dopamine-norepinephrine reuptake inhibitor | Dopamine transporter (DAT); norepinephrine transporter (NET) | |
| OROS MPH Tablets | OROS MPH Tablets | Ortho-McNeil Janssen Scientific Affairs, LLC | marketed | Central nervous system stimulant; dopamine-norepinephrine reuptake inhibitor | Dopamine transporter (DAT); norepinephrine transporter (NET) | |
| Active bupropion + counseling | Active bupropion + counseling | University of Wisconsin, Madison | marketed | Antidepressant (dopamine-norepinephrine reuptake inhibitor) | Dopamine transporter (DAT), Norepinephrine transporter (NET) | |
| drops intilation (Taponoto ® ) | drops intilation (Taponoto ® ) | Hospital Clinic of Barcelona | marketed | Dopamine-norepinephrine reuptake inhibitor | ||
| Drug: PRC-063 | Drug: PRC-063 | Rhodes Pharmaceuticals, L.P. | phase 3 | Stimulant; dopamine-norepinephrine reuptake inhibitor | Dopamine transporter (DAT); norepinephrine transporter (NET) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Central nervous system stimulant; dopamine-norepinephrine reuptake inhibitor class)
- Ortho-McNeil Janssen Scientific Affairs, LLC · 2 drugs in this class
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- OROS MPH CI watch — RSS
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Cite this brief
Drug Landscape (2026). OROS MPH — Competitive Intelligence Brief. https://druglandscape.com/ci/oros-mph. Accessed 2026-05-13.
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