Who are olopatadine (OLO)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Morphine-Promethazine, Diphenhydramine 5%, Olopatadine Nasal Spray, Fluticasone furoate and fexofenadine, Fluticasone/Azelastine nasal spray, alcaftadine 0.25% ophthalmic solution.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

olopatadine (OLO) — Competitive Intelligence Brief

olopatadine (OLO) (olopatadine (OLO)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Selective H1-receptor antagonist / mast cell stabilizer. Area: Allergy / Immunology.

marketed Selective H1-receptor antagonist / mast cell stabilizer H1 histamine receptor Allergy / Immunology Small molecule Live · refreshed every 30 min

Target snapshot

olopatadine (OLO) (olopatadine (OLO)) — University of Chicago. Olopatadine is a selective H1-receptor antagonist and mast cell stabilizer that blocks histamine-mediated allergic responses.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
olopatadine (OLO) TARGET	olopatadine (OLO)	University of Chicago	marketed	Selective H1-receptor antagonist / mast cell stabilizer	H1 histamine receptor
Morphine-Promethazine	Morphine-Promethazine	Tel-Aviv Sourasky Medical Center	marketed	Opioid analgesic combination	Mu-opioid receptor (morphine); H1 histamine receptor (promethazine)
Diphenhydramine 5%	Diphenhydramine 5%	Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology	marketed	H1 receptor antagonist (first-generation antihistamine)	H1 histamine receptor
Olopatadine Nasal Spray	Olopatadine Nasal Spray	ORA, Inc.	marketed	Selective H1-receptor antagonist / mast cell stabilizer	H1 histamine receptor
Fluticasone furoate and fexofenadine	Fluticasone furoate and fexofenadine	GlaxoSmithKline	marketed	Intranasal corticosteroid and antihistamine combination	Glucocorticoid receptor (fluticasone furoate); H1 histamine receptor (fexofenadine)
Fluticasone/Azelastine nasal spray	Fluticasone/Azelastine nasal spray	University of Chicago	marketed	Intranasal corticosteroid/antihistamine combination	Glucocorticoid receptor; H1 histamine receptor
alcaftadine 0.25% ophthalmic solution	alcaftadine 0.25% ophthalmic solution	Allergan	marketed	Selective H1-receptor antagonist	H1 histamine receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Selective H1-receptor antagonist / mast cell stabilizer class)

ORA, Inc. · 1 drug in this class
University of Chicago · 1 drug in this class

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Cite this brief

Drug Landscape (2026). olopatadine (OLO) — Competitive Intelligence Brief. https://druglandscape.com/ci/olopatadine-olo. Accessed 2026-05-16.

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