Who are Opdivo's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Zynyz, ZYNYZ, Pembrolizuma, Tevimbra, Loqtorzi, Jemperli.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Opdivo — Competitive Intelligence Brief

Opdivo (nivolumab) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Programmed Death Receptor-1 Blocking Antibody [EPC]. Area: Oncology.

marketed Programmed Death Receptor-1 Blocking Antibody [EPC] Programmed cell death protein 1 Oncology Monoclonal antibody Live · refreshed every 30 min

Target snapshot

Opdivo (nivolumab) — Bristol-Myers Squibb. Opdivo works by blocking the PD-1 receptor on immune cells, allowing them to attack cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Opdivo TARGET	nivolumab	Bristol-Myers Squibb	marketed	Programmed Death Receptor-1 Blocking Antibody [EPC]	Programmed cell death protein 1	2014-01-01
Zynyz	RETIFANLIMAB	Incyte Corp	marketed	Programmed Death Receptor-1 Blocking Antibody [EPC]	Programmed cell death protein 1	2023-01-01
ZYNYZ	RETIFANLIMAB-DLWR	INCYTE CORP	marketed	Programmed Death Receptor-1 Blocking Antibody [EPC]	Programmed cell death protein 1
Pembrolizuma	Pembrolizuma	Memorial Sloan Kettering Cancer Center	marketed		Programmed cell death protein 1
Tevimbra	TISLELIZUMAB	Beigene	marketed	Programmed Death Receptor-1 Blocking Antibody [EPC]	Pd-1	2025-01-01
Loqtorzi	TORIPALIMAB	Coherus Biosciences Inc	marketed	Programmed Death Receptor-1 Blocking Antibody [EPC]	Pd-1	2024-01-01
Jemperli	DOSTARLIMAB	GSK	marketed	Programmed Death Receptor-1 Blocking Antibody [EPC]	PD-1	2021-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Programmed Death Receptor-1 Blocking Antibody [EPC] class)

· 1 drug in this class
BEIGENE · 1 drug in this class
BRISTOL MYERS SQUIBB · 1 drug in this class
BRISTOL-MYERS SQUIBB · 1 drug in this class
Beigene · 1 drug in this class
Beijing Tongren Hospital · 1 drug in this class
Bristol-Myers Squibb · 1 drug in this class
Coherus Biosciences Inc · 1 drug in this class
GLAXOSMITHKLINE · 1 drug in this class
GSK · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Opdivo — Competitive Intelligence Brief. https://druglandscape.com/ci/nivolumab. Accessed 2026-05-14.

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