Who are Nicotinic acid (niacin)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Niacin plus laropiprant, Omega-3 Supplementation, nicotinic acid/laropiprant, Niacin Extended Release/Lovastatin, Niacin/ Laropiprant, omega-3-fatty acids (Omegaven).

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Last reviewed 2026-05-16 · How we verify

Nicotinic acid (niacin) — Competitive Intelligence Brief

Nicotinic acid (niacin) (Nicotinic acid (niacin)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Lipid-modifying agent; B vitamin. Area: Cardiovascular.

marketed Lipid-modifying agent; B vitamin GPR109A (HM74A receptor) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Nicotinic acid (niacin) (Nicotinic acid (niacin)) — Charite University, Berlin, Germany. Nicotinic acid activates GPR109A receptors on immune cells and adipocytes to reduce lipolysis, decrease free fatty acid release, and lower triglycerides and LDL cholesterol while raising HDL cholesterol.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Nicotinic acid (niacin) TARGET	Nicotinic acid (niacin)	Charite University, Berlin, Germany	marketed	Lipid-modifying agent; B vitamin	GPR109A (HM74A receptor)
Niacin plus laropiprant	Niacin plus laropiprant	Institut Investigacio Sanitaria Pere Virgili	marketed	Lipid-modifying agent combination	DP1 receptor (laropiprant component); niacin acts on GPR109A and other pathways
Omega-3 Supplementation	Omega-3 Supplementation	Università degli Studi di Brescia	marketed	Dietary supplement / Lipid-modifying agent	GPR120, GPR40, PPAR-γ, NF-κB signaling pathway
nicotinic acid/laropiprant	nicotinic acid/laropiprant	Manchester University NHS Foundation Trust	marketed	Lipid-modifying agent / Antilipemic	GPR109A receptor (laropiprant component); nicotinic acid acts on multiple lipid metabolism pathways
Niacin Extended Release/Lovastatin	Niacin Extended Release/Lovastatin	In His Image	marketed	Statin/Niacin combination; Lipid-modifying agent	HMG-CoA reductase (lovastatin); GPR109A/PUMA-G receptor (niacin)
Niacin/ Laropiprant	Niacin/ Laropiprant	Ludwig-Maximilians - University of Munich	marketed	Lipid-modifying agent; prostaglandin D2 receptor antagonist	DGAT2 (niacin); DP1 prostaglandin receptor (laropiprant)
omega-3-fatty acids (Omegaven)	omega-3-fatty acids (Omegaven)	Li Shin Hospital	marketed	Lipid-modifying agent; anti-inflammatory

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Lipid-modifying agent; B vitamin class)

Charite University, Berlin, Germany · 1 drug in this class
Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Nicotinic acid (niacin) — Competitive Intelligence Brief. https://druglandscape.com/ci/nicotinic-acid-niacin. Accessed 2026-05-16.

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