Who are N-Acetyl Cysteine (NAC)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): IV N-acetylcysteine, IV N-Acetyl Cystein, Inhaled Reduced Glutathione.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

N-Acetyl Cysteine (NAC) — Competitive Intelligence Brief

N-Acetyl Cysteine (NAC) (N-Acetyl Cysteine (NAC)) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antioxidant / Mucolytic agent. Area: Respiratory, Toxicology, Nephrology, Hepatology.

marketed Antioxidant / Mucolytic agent Glutathione synthesis pathway; reactive oxygen species (non-specific) Respiratory, Toxicology, Nephrology, Hepatology Small molecule Live · refreshed every 30 min

Target snapshot

N-Acetyl Cysteine (NAC) (N-Acetyl Cysteine (NAC)) — The Aurum Institute NPC. N-Acetyl Cysteine (NAC) replenishes intracellular glutathione, a major antioxidant, and provides a free thiol group that directly scavenges reactive oxygen species and electrophiles.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
N-Acetyl Cysteine (NAC) TARGET	N-Acetyl Cysteine (NAC)	The Aurum Institute NPC	marketed	Antioxidant / Mucolytic agent	Glutathione synthesis pathway; reactive oxygen species (non-specific)
IV N-acetylcysteine	IV N-acetylcysteine	Medical University of South Carolina	phase 3	Antioxidant / Mucolytic agent	Glutathione synthesis pathway; free radical scavenger
IV N-Acetyl Cystein	IV N-Acetyl Cystein	Imam Khomeini Hospital	phase 3	Antioxidant / Mucolytic agent	Glutathione synthesis pathway; free radicals and reactive oxygen species
Inhaled Reduced Glutathione	Inhaled Reduced Glutathione	Serafino A. Marsico	phase 3	Antioxidant / Mucolytic agent	Glutathione (endogenous antioxidant system)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antioxidant / Mucolytic agent class)

Imam Khomeini Hospital · 1 drug in this class
Medical University of South Carolina · 1 drug in this class
Serafino A. Marsico · 1 drug in this class
The Aurum Institute NPC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). N-Acetyl Cysteine (NAC) — Competitive Intelligence Brief. https://druglandscape.com/ci/n-acetyl-cysteine-nac. Accessed 2026-05-16.

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