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MSI-78 — Competitive Intelligence Brief
phase 3
Antimicrobial peptide
Bacterial cell membrane
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
MSI-78 (MSI-78) — Abeona Therapeutics, Inc. MSI-78 is an antimicrobial peptide that disrupts bacterial cell membranes to treat infections caused by multidrug-resistant pathogens.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| MSI-78 TARGET | MSI-78 | Abeona Therapeutics, Inc | phase 3 | Antimicrobial peptide | Bacterial cell membrane | |
| Silvadene | Silver Sulfadiazine | Pfizer | marketed | sulfonamide antimicrobial | bacterial cell membrane and cell wall | 1973-01-01 |
| Benzalkonium Chloride-Benzocaine Topical | Benzalkonium Chloride-Benzocaine Topical | Medice Arzneimittel Pütter GmbH & Co KG | marketed | Topical antimicrobial-anesthetic combination | Bacterial cell membranes (benzalkonium); sodium channels (benzocaine) | |
| Epiduo® Gel right face | Epiduo® Gel right face | GWT-TUD GmbH | marketed | Retinoid + peroxide combination | Retinoic acid receptor (adapalene); bacterial cell membrane disruption (benzoyl peroxide) | |
| Sensodyne Sensitivity & Gum | Sensodyne Sensitivity & Gum | HALEON | marketed | Desensitizing toothpaste with antimicrobial and anti-inflammatory agents | Sensory nerve fibers (potassium nitrate); bacterial cell membranes and gum tissue (stannous compounds) | |
| Stannous Fluoride Dentifrice | Stannous Fluoride Dentifrice | Procter and Gamble | marketed | Topical fluoride dentifrice | Tooth enamel (hydroxyapatite); bacterial cell membranes | |
| Neutrogena Rapid Clear® | Neutrogena Rapid Clear® | GlaxoSmithKline | marketed | Topical antimicrobial/keratolytic agent | Cutibacterium acnes (bacterial cell membranes and proteins) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antimicrobial peptide class)
- Abeona Therapeutics, Inc · 1 drug in this class
- Dipexium Pharmaceuticals, Inc. · 1 drug in this class
- Guangzhou Yipinhong Pharmaceutical CO.,LTD · 1 drug in this class
- Maruho Co., Ltd. · 1 drug in this class
- Tufts Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). MSI-78 — Competitive Intelligence Brief. https://druglandscape.com/ci/msi-78. Accessed 2026-05-13.
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