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MSI-78 — Competitive Intelligence Brief

MSI-78 (MSI-78) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimicrobial peptide. Area: Infectious Disease.

phase 3 Antimicrobial peptide Bacterial cell membrane Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

MSI-78 (MSI-78) — Abeona Therapeutics, Inc. MSI-78 is an antimicrobial peptide that disrupts bacterial cell membranes to treat infections caused by multidrug-resistant pathogens.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
MSI-78 TARGET MSI-78 Abeona Therapeutics, Inc phase 3 Antimicrobial peptide Bacterial cell membrane
Silvadene Silver Sulfadiazine Pfizer marketed sulfonamide antimicrobial bacterial cell membrane and cell wall 1973-01-01
Benzalkonium Chloride-Benzocaine Topical Benzalkonium Chloride-Benzocaine Topical Medice Arzneimittel Pütter GmbH & Co KG marketed Topical antimicrobial-anesthetic combination Bacterial cell membranes (benzalkonium); sodium channels (benzocaine)
Epiduo® Gel right face Epiduo® Gel right face GWT-TUD GmbH marketed Retinoid + peroxide combination Retinoic acid receptor (adapalene); bacterial cell membrane disruption (benzoyl peroxide)
Sensodyne Sensitivity & Gum Sensodyne Sensitivity & Gum HALEON marketed Desensitizing toothpaste with antimicrobial and anti-inflammatory agents Sensory nerve fibers (potassium nitrate); bacterial cell membranes and gum tissue (stannous compounds)
Stannous Fluoride Dentifrice Stannous Fluoride Dentifrice Procter and Gamble marketed Topical fluoride dentifrice Tooth enamel (hydroxyapatite); bacterial cell membranes
Neutrogena Rapid Clear® Neutrogena Rapid Clear® GlaxoSmithKline marketed Topical antimicrobial/keratolytic agent Cutibacterium acnes (bacterial cell membranes and proteins)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimicrobial peptide class)

  1. Abeona Therapeutics, Inc · 1 drug in this class
  2. Dipexium Pharmaceuticals, Inc. · 1 drug in this class
  3. Guangzhou Yipinhong Pharmaceutical CO.,LTD · 1 drug in this class
  4. Maruho Co., Ltd. · 1 drug in this class
  5. Tufts Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). MSI-78 — Competitive Intelligence Brief. https://druglandscape.com/ci/msi-78. Accessed 2026-05-13.

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