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Neutrogena Rapid Clear®

GlaxoSmithKline · FDA-approved active Small molecule

Neutrogena Rapid Clear® contains benzoyl peroxide, which kills acne-causing bacteria and reduces sebum production on the skin.

Neutrogena Rapid Clear contains benzoyl peroxide, which kills acne-causing bacteria and reduces sebum production on the skin. Used for Acne vulgaris (mild to moderate).

At a glance

Generic nameNeutrogena Rapid Clear®
SponsorGlaxoSmithKline
Drug classTopical antimicrobial/keratolytic agent
TargetCutibacterium acnes (bacterial cell membranes and proteins)
ModalitySmall molecule
Therapeutic areaDermatology
PhaseFDA-approved

Mechanism of action

Benzoyl peroxide is a topical antimicrobial and keratolytic agent that penetrates the skin to eliminate Cutibacterium acnes (formerly Propionibacterium acnes) bacteria in follicles and sebaceous glands. It also promotes desquamation and reduces comedone formation by normalizing skin cell turnover. The mechanism is bactericidal rather than bacteriostatic, making resistance development unlikely.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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