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Misoprostol (given vaginally) — Competitive Intelligence Brief
marketed
Prostaglandin analogue
Prostaglandin E1 receptor (EP receptor)
Obstetrics/Gynecology
Small molecule
Live · refreshed every 30 min
Target snapshot
Misoprostol (given vaginally) (Misoprostol (given vaginally)) — Hawler Medical University. Misoprostol is a prostaglandin E1 analogue that binds to prostaglandin receptors to increase uterine contractions and promote cervical ripening and dilation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Misoprostol (given vaginally) TARGET | Misoprostol (given vaginally) | Hawler Medical University | marketed | Prostaglandin analogue | Prostaglandin E1 receptor (EP receptor) | |
| Misoprostol, modified-release pessary | Misoprostol, modified-release pessary | Tampere University Hospital | marketed | Prostaglandin analogue | Prostaglandin E1 receptor (EP receptor) | |
| tafluprost and dorzolamide/timolol | tafluprost and dorzolamide/timolol | Aristotle University Of Thessaloniki | marketed | Prostaglandin analogue / carbonic anhydrase inhibitor / beta-blocker combination | Prostaglandin F receptor (FP receptor), carbonic anhydrase II, beta-1 and beta-2 adrenergic receptors | |
| Misoprostol, per-oral tablets | Misoprostol, per-oral tablets | Tampere University Hospital | marketed | Prostaglandin analogue | Prostaglandin E1 receptor (EP receptor) | |
| Preservative-Free Tafluprost or vehicle | Preservative-Free Tafluprost or vehicle | Merck Sharp & Dohme LLC | phase 3 | Prostaglandin analogue | Prostaglandin F2α receptor | |
| Tafluprost ophthalmic solution 0.0015% | Tafluprost ophthalmic solution 0.0015% | Santen Pharmaceutical Co., Ltd. | phase 3 | Prostaglandin analogue | Prostaglandin F2α receptor | |
| Travoprost/ Timolol/ Azopt/ Brimonidine | Travoprost/ Timolol/ Azopt/ Brimonidine | Singapore Eye Research Institute | phase 3 | Prostaglandin analogue, Beta blocker, Carbonic anhydrase inhibitor, Alpha-2 adrenergic agonist | Prostaglandin F2α receptor, Beta-adrenergic receptor, Carbonic anhydrase, Alpha-2 adrenergic receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Prostaglandin analogue class)
- Tampere University Hospital · 2 drugs in this class
- Allergan · 1 drug in this class
- Hawler Medical University · 1 drug in this class
- Ain Shams University · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- Santen Pharmaceutical Co., Ltd. · 1 drug in this class
- Mati Therapeutics Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Misoprostol (given vaginally) — Competitive Intelligence Brief. https://druglandscape.com/ci/misoprostol-given-vaginally. Accessed 2026-05-13.
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