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Mifepristone + Misoprostol — Competitive Intelligence Brief
marketed
Progesterone receptor antagonist + prostaglandin analog combination
Progesterone receptor (PR); prostaglandin E1 receptor (EP receptor)
Reproductive Health / Gynecology
Small molecule
Live · refreshed every 30 min
Target snapshot
Mifepristone + Misoprostol (Mifepristone + Misoprostol) — Gynuity Health Projects. Mifepristone blocks progesterone receptors to stop pregnancy maintenance, while misoprostol induces uterine contractions to expel the pregnancy.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Mifepristone + Misoprostol TARGET | Mifepristone + Misoprostol | Gynuity Health Projects | marketed | Progesterone receptor antagonist + prostaglandin analog combination | Progesterone receptor (PR); prostaglandin E1 receptor (EP receptor) | |
| Medical abortion | Medical abortion | Reproductive Health Training Center of the Republic of Moldova | marketed | Progesterone receptor antagonist + prostaglandin analog combination | Progesterone receptor (PR); prostaglandin receptors (EP1, EP2, EP3, FP) | |
| mifepristone and misopristol | mifepristone and misopristol | Hadassah Medical Organization | marketed | Progesterone receptor antagonist + prostaglandin analog combination | Progesterone receptor (PR) and prostaglandin E1 receptor (EP receptor) | |
| Mifepristone plus two doses Misoprostol | Mifepristone plus two doses Misoprostol | Planned Parenthood League of Massachusetts | phase 3 | Progesterone receptor antagonist + prostaglandin analog combination | Progesterone receptor (PR); prostaglandin E1 receptor (EP receptor) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Progesterone receptor antagonist + prostaglandin analog combination class)
- Gynuity Health Projects · 1 drug in this class
- Hadassah Medical Organization · 1 drug in this class
- Planned Parenthood League of Massachusetts · 1 drug in this class
- Reproductive Health Training Center of the Republic of Moldova · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Mifepristone + Misoprostol — Competitive Intelligence Brief. https://druglandscape.com/ci/mifepristone-misoprostol. Accessed 2026-05-16.
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