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Magnesium Sulfate high dose — Competitive Intelligence Brief

Magnesium Sulfate high dose (Magnesium Sulfate high dose) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NMDA receptor antagonist / Anticonvulsant. Area: Neurology.

phase 3 NMDA receptor antagonist / Anticonvulsant NMDA receptor Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Magnesium Sulfate high dose (Magnesium Sulfate high dose) — Dr Olu Bamgbade, MD, FRCPC. High-dose magnesium sulfate acts as a NMDA receptor antagonist and stabilizes neuronal membranes, reducing excitotoxicity and seizure activity.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Magnesium Sulfate high dose TARGET Magnesium Sulfate high dose Dr Olu Bamgbade, MD, FRCPC phase 3 NMDA receptor antagonist / Anticonvulsant NMDA receptor
Namenda MEMANTINE AbbVie marketed N-methyl-D-aspartate Receptor Antagonist Glutamate NMDA receptor; GRIN1/GRIN2A 2003-01-01
Felbatol FELBAMATE Mylan Speciality Lp marketed Anti-epileptic Agent [EPC] NMDA receptor-ionophore complex 1993-01-01
QUINIDINE QUINIDINE marketed sigma-1 receptor, NMDA receptor, CYP2D6 1950-01-01
Methadone Hydrochloride METHADONE Specgx Llc marketed Opioid Agonist mu-opioid receptors, NMDA receptor 1947-01-01
DXM + Propofol DXM + Propofol Seoul National University Hospital marketed Dissociative anesthetic combination NMDA receptor (DXM); GABA-A receptor (propofol)
Ketamine and Midazolam Ketamine and Midazolam Kanuni Sultan Suleyman Training and Research Hospital marketed Dissociative anesthetic and benzodiazepine combination NMDA receptor (ketamine); GABA-A receptor (midazolam)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NMDA receptor antagonist / Anticonvulsant class)

  1. Dr Olu Bamgbade, MD, FRCPC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Magnesium Sulfate high dose — Competitive Intelligence Brief. https://druglandscape.com/ci/magnesium-sulfate-high-dose. Accessed 2026-05-17.

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