Last reviewed · How we verify
Magnesium Sulfate high dose — Competitive Intelligence Brief
phase 3
NMDA receptor antagonist / Anticonvulsant
NMDA receptor
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Magnesium Sulfate high dose (Magnesium Sulfate high dose) — Dr Olu Bamgbade, MD, FRCPC. High-dose magnesium sulfate acts as a NMDA receptor antagonist and stabilizes neuronal membranes, reducing excitotoxicity and seizure activity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Magnesium Sulfate high dose TARGET | Magnesium Sulfate high dose | Dr Olu Bamgbade, MD, FRCPC | phase 3 | NMDA receptor antagonist / Anticonvulsant | NMDA receptor | |
| Namenda | MEMANTINE | AbbVie | marketed | N-methyl-D-aspartate Receptor Antagonist | Glutamate NMDA receptor; GRIN1/GRIN2A | 2003-01-01 |
| Felbatol | FELBAMATE | Mylan Speciality Lp | marketed | Anti-epileptic Agent [EPC] | NMDA receptor-ionophore complex | 1993-01-01 |
| QUINIDINE | QUINIDINE | marketed | sigma-1 receptor, NMDA receptor, CYP2D6 | 1950-01-01 | ||
| Methadone Hydrochloride | METHADONE | Specgx Llc | marketed | Opioid Agonist | mu-opioid receptors, NMDA receptor | 1947-01-01 |
| DXM + Propofol | DXM + Propofol | Seoul National University Hospital | marketed | Dissociative anesthetic combination | NMDA receptor (DXM); GABA-A receptor (propofol) | |
| Ketamine and Midazolam | Ketamine and Midazolam | Kanuni Sultan Suleyman Training and Research Hospital | marketed | Dissociative anesthetic and benzodiazepine combination | NMDA receptor (ketamine); GABA-A receptor (midazolam) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NMDA receptor antagonist / Anticonvulsant class)
- Dr Olu Bamgbade, MD, FRCPC · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Magnesium Sulfate high dose CI watch — RSS
- Magnesium Sulfate high dose CI watch — Atom
- Magnesium Sulfate high dose CI watch — JSON
- Magnesium Sulfate high dose alone — RSS
- Whole NMDA receptor antagonist / Anticonvulsant class — RSS
Cite this brief
Drug Landscape (2026). Magnesium Sulfate high dose — Competitive Intelligence Brief. https://druglandscape.com/ci/magnesium-sulfate-high-dose. Accessed 2026-05-17.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab