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low molecular weight heparin, 5-FU — Competitive Intelligence Brief
phase 3
Anticoagulant
Factor Xa, Thrombin
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
low molecular weight heparin, 5-FU (low molecular weight heparin, 5-FU) — Shahid Beheshti University of Medical Sciences. Low molecular weight heparin works by inhibiting Factor Xa and thrombin, preventing blood clot formation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| low molecular weight heparin, 5-FU TARGET | low molecular weight heparin, 5-FU | Shahid Beheshti University of Medical Sciences | phase 3 | Anticoagulant | Factor Xa, Thrombin | |
| nadroparin calcium-warfarin sequential anticoagulation | nadroparin calcium-warfarin sequential anticoagulation | Qilu Hospital of Shandong University | marketed | Anticoagulant combination (LMWH + vitamin K antagonist) | Factor Xa, thrombin (nadroparin); vitamin K-dependent clotting factors II, VII, IX, X (warfarin) | |
| Low dose nadroparin | Low dose nadroparin | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | marketed | Low-molecular-weight heparin (LMWH) | Factor Xa, Thrombin (Factor IIa) | |
| Intermediate dose nadroparin | Intermediate dose nadroparin | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | marketed | Low-molecular-weight heparin (LMWH) | Factor Xa, Thrombin (via antithrombin III enhancement) | |
| LMWH+Folic acid | LMWH+Folic acid | Omar Mamdouh Shaaban | marketed | Anticoagulant combination with vitamin supplement | Factor Xa, Thrombin (LMWH component); Dihydrofolate reductase (folic acid component) | |
| Klexane and ASA | Klexane and ASA | University of Helsinki | phase 3 | Low-molecular-weight heparin + antiplatelet agent | Factor Xa, thrombin (enoxaparin); cyclooxygenase (aspirin) | |
| LMWH (Fragmin, dalteparin) | LMWH (Fragmin, dalteparin) | McMaster University | phase 3 | Low-molecular-weight heparin (LMWH) | Factor Xa, Thrombin (Factor IIa), Antithrombin III |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anticoagulant class)
- Fresenius Kabi · 4 drugs in this class
- University of Sao Paulo · 3 drugs in this class
- Beijing Anzhen Hospital · 2 drugs in this class
- San Filippo Neri General Hospital · 2 drugs in this class
- Yong Seog Oh · 2 drugs in this class
- CCRF Consulting Co., Ltd. · 1 drug in this class
- Boston Scientific Corporation · 1 drug in this class
- Beijing Suncadia Pharmaceuticals Co., Ltd · 1 drug in this class
- Faculty Hospital Kralovske Vinohrady · 1 drug in this class
- Deutsches Herzzentrum Muenchen · 1 drug in this class
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Cite this brief
Drug Landscape (2026). low molecular weight heparin, 5-FU — Competitive Intelligence Brief. https://druglandscape.com/ci/low-molecular-weight-heparin-5-fu. Accessed 2026-05-17.
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