Last reviewed · How we verify
LMWH+Folic acid
LMWH+Folic acid is a Anticoagulant combination with vitamin supplement Small molecule drug developed by Omar Mamdouh Shaaban. It is currently FDA-approved for Thromboprophylaxis in pregnancy or thrombophilic disorders, Prevention of venous thromboembolism with folate supplementation. Also known as: (Clexane, Sanofi Aventis, Paris, France).
This combination product uses low-molecular-weight heparin (LMWH) to prevent blood clots and folic acid to support cellular function and reduce homocysteine levels.
This combination product uses low-molecular-weight heparin (LMWH) to prevent blood clots and folic acid to support cellular function and reduce homocysteine levels. Used for Thromboprophylaxis in pregnancy or thrombophilic disorders, Prevention of venous thromboembolism with folate supplementation.
At a glance
| Generic name | LMWH+Folic acid |
|---|---|
| Also known as | (Clexane, Sanofi Aventis, Paris, France) |
| Sponsor | Omar Mamdouh Shaaban |
| Drug class | Anticoagulant combination with vitamin supplement |
| Target | Factor Xa, Thrombin (LMWH component); Dihydrofolate reductase (folic acid component) |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular / Hematology |
| Phase | FDA-approved |
Mechanism of action
LMWH inhibits thrombin and Factor Xa, preventing thrombosis through anticoagulation. Folic acid is a B vitamin essential for DNA synthesis and homocysteine metabolism, potentially reducing cardiovascular risk. The combination may be used in pregnancy or thrombophilic conditions where both anticoagulation and folate supplementation are therapeutically beneficial.
Approved indications
- Thromboprophylaxis in pregnancy or thrombophilic disorders
- Prevention of venous thromboembolism with folate supplementation
Common side effects
- Bleeding
- Thrombocytopenia
- Injection site reactions
- Gastrointestinal upset (folic acid)
Key clinical trials
- A Therapeutic Protocol in Previous Failed ART Patients With High Total NK Cells (PHASE2)
- Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies (PHASE4)
- Chemotherapy With or Without Enoxaparin in Pancreatic Cancer (PHASE2, PHASE3)
- Effectiveness of Dalteparin Therapy as Intervention in Recurrent Pregnancy Loss (PHASE3)
- FOLFIRI + Bevacizumab With or Without Dalteparin in First Line Treatment of Advanced Colorectal Cancer (PHASE2)
- Pilot Safety Trial of Chemotherapy and Use of Heparin in Patients With Pancreatic Cancer (PHASE1, PHASE2)
- Cisplatin With Alimta or Gemcitabine in Long Infusion for Mesothelioma (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- LMWH+Folic acid CI brief — competitive landscape report
- LMWH+Folic acid updates RSS · CI watch RSS
- Omar Mamdouh Shaaban portfolio CI
Frequently asked questions about LMWH+Folic acid
What is LMWH+Folic acid?
How does LMWH+Folic acid work?
What is LMWH+Folic acid used for?
Who makes LMWH+Folic acid?
Is LMWH+Folic acid also known as anything else?
What drug class is LMWH+Folic acid in?
What development phase is LMWH+Folic acid in?
What are the side effects of LMWH+Folic acid?
What does LMWH+Folic acid target?
Related
- Drug class: All Anticoagulant combination with vitamin supplement drugs
- Target: All drugs targeting Factor Xa, Thrombin (LMWH component); Dihydrofolate reductase (folic acid component)
- Manufacturer: Omar Mamdouh Shaaban — full pipeline
- Therapeutic area: All drugs in Cardiovascular / Hematology
- Indication: Drugs for Thromboprophylaxis in pregnancy or thrombophilic disorders
- Indication: Drugs for Prevention of venous thromboembolism with folate supplementation
- Also known as: (Clexane, Sanofi Aventis, Paris, France)
- Compare: LMWH+Folic acid vs similar drugs
- Pricing: LMWH+Folic acid cost, discount & access