Who are Losartan and amlodipine and hydrochlorothiazide's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): olmesartan/amlodipine + hydrochlorothiazide, if necessary., irbesartan, amlodipine and hydrochlorothiazide.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Losartan and amlodipine and hydrochlorothiazide — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Losartan and amlodipine and hydrochlorothiazide (Losartan and amlodipine and hydrochlorothiazide) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antihypertensive combination (ARB + calcium channel blocker + thiazide diuretic). Area: Cardiovascular.

marketed Antihypertensive combination (ARB + calcium channel blocker + thiazide diuretic) Angiotensin II type 1 receptor (AT1R), L-type calcium channels, sodium-chloride cotransporter Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Losartan and amlodipine and hydrochlorothiazide (Losartan and amlodipine and hydrochlorothiazide) — Hotel Dieu de France Hospital. This triple-combination antihypertensive reduces blood pressure through three complementary mechanisms: angiotensin II receptor blockade, calcium channel inhibition, and thiazide diuresis.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Losartan and amlodipine and hydrochlorothiazide TARGET	Losartan and amlodipine and hydrochlorothiazide	Hotel Dieu de France Hospital	marketed	Antihypertensive combination (ARB + calcium channel blocker + thiazide diuretic)	Angiotensin II type 1 receptor (AT1R), L-type calcium channels, sodium-chloride cotransporter
olmesartan/amlodipine + hydrochlorothiazide, if necessary.	olmesartan/amlodipine + hydrochlorothiazide, if necessary.	Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company	marketed	Antihypertensive combination (ARB + calcium channel blocker + thiazide diuretic)	Angiotensin II type 1 receptor (AT1R), L-type calcium channels, sodium-chloride cotransporter (NCC)
irbesartan, amlodipine and hydrochlorothiazide	irbesartan, amlodipine and hydrochlorothiazide	Assistance Publique - Hôpitaux de Paris	marketed	Antihypertensive combination (ARB + calcium channel blocker + thiazide diuretic)	Angiotensin II type 1 receptor (AT1R), L-type calcium channels, sodium-chloride cotransporter

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antihypertensive combination (ARB + calcium channel blocker + thiazide diuretic) class)

Assistance Publique - Hôpitaux de Paris · 1 drug in this class
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company · 1 drug in this class
Hotel Dieu de France Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Losartan and amlodipine and hydrochlorothiazide — Competitive Intelligence Brief. https://druglandscape.com/ci/losartan-and-amlodipine-and-hydrochlorothiazide. Accessed 2026-05-16.

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