L-Histidine — Competitive Intelligence Brief

L-Histidine (L-Histidine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Amino acid supplement. Area: Nutritional/Metabolic.

marketed Amino acid supplement Nutritional/Metabolic Small molecule

Target snapshot

L-Histidine (L-Histidine) — University of Miami. L-Histidine is an essential amino acid that serves as a precursor for histamine and other bioactive compounds involved in immune regulation, gastric acid secretion, and vasodilation.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
L-Histidine TARGET	L-Histidine	University of Miami	marketed	Amino acid supplement
L-arginine (L-arginine Veyron)	L-arginine (L-arginine Veyron)	University Hospital, Strasbourg, France	marketed	Amino acid supplement	Nitric oxide synthase (substrate)
L-arginine + heme arginate	L-arginine + heme arginate	Radboud University Medical Center	marketed	Amino acid supplement / Nitric oxide donor	Nitric oxide synthase (NOS); hemoglobin
keto-amino acids	keto-amino acids	YUAN Wei-jie	marketed	Amino acid supplement / Nutritional therapeutic
Keto Acid	Keto Acid	Peking University First Hospital	marketed	Amino acid supplement / Nutritional agent
L-alanine	L-alanine	Keith D Lindor, M.D.	marketed	Amino acid supplement
L Carnitine ( low dose)	L Carnitine ( low dose)	Ain Shams University	marketed	Amino acid supplement / Metabolic agent	Carnitine palmitoyltransferase (CPT) system

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Amino acid supplement class)

1. Air Force Military Medical University, China · 1 drug in this class
2. Elijah W. Stommel · 1 drug in this class
3. Hadassah Medical Organization · 1 drug in this class
4. Keith D Lindor, M.D. · 1 drug in this class
5. McMaster University · 1 drug in this class
6. The University of Texas at Arlington · 1 drug in this class
7. Ukrainian Medical Stomatological Academy · 1 drug in this class
8. University Hospital, Strasbourg, France · 1 drug in this class
9. University of Colorado, Denver · 1 drug in this class
10. University of Miami · 1 drug in this class