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Ivermectin (reference) — Competitive Intelligence Brief
phase 3
Antiparasitic agent
Glutamate-gated chloride channels (GluCl)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Ivermectin (reference) (Ivermectin (reference)) — Padagis LLC. Ivermectin binds to glutamate-gated chloride channels in parasitic organisms, causing paralysis and death of the parasite.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ivermectin (reference) TARGET | Ivermectin (reference) | Padagis LLC | phase 3 | Antiparasitic agent | Glutamate-gated chloride channels (GluCl) | |
| Antimoniate of N-methylglucamine | Antimoniate of N-methylglucamine | University of Brasilia | marketed | Antiparasitic agent | Leishmania glycolytic enzymes and mitochondrial function | |
| Pyrimethamine (PYR) | Pyrimethamine (PYR) | Erasmus Medical Center | marketed | Antifolate antimalarial and antiparasitic agent | Dihydrofolate reductase (DHFR) | |
| Ivermectin 1% cream | Ivermectin 1% cream | Insel Gruppe AG, University Hospital Bern | marketed | Antiparasitic agent | Glutamate-gated chloride channels | |
| ''albendazole'' and ''ivermectin'' | ''albendazole'' and ''ivermectin'' | Centre d'Appui à la lutte contre la Maladie | marketed | Antihelmintic/Antiparasitic agents | β-tubulin (albendazole); glutamate-gated chloride channels (ivermectin) | |
| Ivermectin 1% cream (IVM) | Ivermectin 1% cream (IVM) | Galderma R&D | marketed | Antiparasitic agent | Glutamate-gated chloride channels (invertebrate-specific) | |
| Atovaquone Oral Suspension | Atovaquone Oral Suspension | University of Oxford | marketed | Antiparasitic agent | Cytochrome bc1 complex (Complex III) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiparasitic agent class)
- Actavis Inc. · 2 drugs in this class
- Galderma R&D · 1 drug in this class
- Insel Gruppe AG, University Hospital Bern · 1 drug in this class
- Padagis LLC · 1 drug in this class
- U.S. Army Medical Research and Development Command · 1 drug in this class
- University of Brasilia · 1 drug in this class
- University of Oxford · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ivermectin (reference) — Competitive Intelligence Brief. https://druglandscape.com/ci/ivermectin-reference. Accessed 2026-05-13.
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