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Ivermectin 1% cream — Competitive Intelligence Brief
marketed
Antiparasitic agent
Glutamate-gated chloride channels
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Ivermectin 1% cream (Ivermectin 1% cream) — Insel Gruppe AG, University Hospital Bern. Ivermectin binds to glutamate-gated chloride channels in parasites and arthropods, causing paralysis and death of the organisms.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ivermectin 1% cream TARGET | Ivermectin 1% cream | Insel Gruppe AG, University Hospital Bern | marketed | Antiparasitic agent | Glutamate-gated chloride channels | |
| ''albendazole'' and ''ivermectin'' | ''albendazole'' and ''ivermectin'' | Centre d'Appui à la lutte contre la Maladie | marketed | Antihelmintic/Antiparasitic agents | β-tubulin (albendazole); glutamate-gated chloride channels (ivermectin) | |
| Ivermectin 1% cream (IVM) | Ivermectin 1% cream (IVM) | Galderma R&D | marketed | Antiparasitic agent | Glutamate-gated chloride channels (invertebrate-specific) | |
| Oral ivermectin | Oral ivermectin | University of Oxford | marketed | Macrocyclic lactone antiparasitic | Glutamate-gated chloride channels (GluCl) | |
| Ivermectin + colchicine | Ivermectin + colchicine | Ain Shams University | marketed | Antiparasitic + anti-inflammatory combination | Glutamate-gated chloride channels (ivermectin); tubulin/microtubules (colchicine) | |
| Ivermectin 0.1% Metronidazole 1% | Ivermectin 0.1% Metronidazole 1% | Universidad Nacional de Colombia | phase 3 | Antiparasitic/Antimicrobial combination | Glutamate-gated chloride channels (ivermectin); DNA/anaerobic metabolism (metronidazole) | |
| Ivermectin (reference) | Ivermectin (reference) | Padagis LLC | phase 3 | Antiparasitic agent | Glutamate-gated chloride channels (GluCl) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiparasitic agent class)
- Actavis Inc. · 2 drugs in this class
- Galderma R&D · 1 drug in this class
- Insel Gruppe AG, University Hospital Bern · 1 drug in this class
- Padagis LLC · 1 drug in this class
- U.S. Army Medical Research and Development Command · 1 drug in this class
- University of Brasilia · 1 drug in this class
- University of Oxford · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ivermectin 1% cream — Competitive Intelligence Brief. https://druglandscape.com/ci/ivermectin-1-cream. Accessed 2026-06-10.
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