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Isoniazid (Rifinah) — Competitive Intelligence Brief
marketed
Antituberculous agent
Enoyl-ACP reductase (InhA)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Isoniazid (Rifinah) (Isoniazid (Rifinah)) — National Taiwan University Hospital. Isoniazid inhibits mycobacterial cell wall synthesis by blocking mycolic acid production, which is essential for Mycobacterium tuberculosis survival.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Isoniazid (Rifinah) TARGET | Isoniazid (Rifinah) | National Taiwan University Hospital | marketed | Antituberculous agent | Enoyl-ACP reductase (InhA) | |
| Isoniazid (INH) | Isoniazid (INH) | National Institutes of Health Clinical Center (CC) | marketed | Antituberculous agent | InhA (enoyl-ACP reductase) | |
| Rifampin/isoniazid FDC | Rifampin/isoniazid FDC | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Antituberculous agent (fixed-dose combination) | Bacterial RNA polymerase (rifampin); mycolic acid biosynthesis (isoniazid) | |
| Isoniazid Aminosalicylate Tablets | Isoniazid Aminosalicylate Tablets | Shanghai Pulmonary Hospital, Shanghai, China | marketed | Antituberculous agent combination | Mycobacterial catalase-peroxidase (KatG), mycolic acid synthesis, folate metabolism | |
| Isoniazid with Ethambutol | Isoniazid with Ethambutol | Tuberculosis Research Centre, India | phase 3 | Antituberculous agents | InhA (isoniazid); arabinosyl transferases (ethambutol) | |
| Isoniazid (H) | Isoniazid (H) | University College, London | phase 3 | Nicotinamide analog; first-line antituberculous agent | Enoyl-ACP reductase (InhA); catalase-peroxidase (KatG) | |
| Pyrazinamide Oral Product | Pyrazinamide Oral Product | Wits Health Consortium (Pty) Ltd | phase 3 | Antituberculous agent | Pantothenate synthetase (PanC); pyrazinamidase activation required |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antituberculous agent class)
- National Taiwan University Hospital · 2 drugs in this class
- Wits Health Consortium (Pty) Ltd · 2 drugs in this class
- National Institutes of Health Clinical Center (CC) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Isoniazid (Rifinah) — Competitive Intelligence Brief. https://druglandscape.com/ci/isoniazid-rifinah. Accessed 2026-05-16.
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