Who are Intraoperative infusion of dexmedetomidine's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Randomization of Propofol or Dexmedetomidine, Clonidine Pill, Brimonidine 0.33% gel (Br), Ropivacaine + Dexmedetomidine, Fexofenadine HCL and pseudoephedrine HCL, brimonidine topical gel 0.33% & SOC.

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Last reviewed 2026-05-17 · How we verify

Intraoperative infusion of dexmedetomidine — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intraoperative infusion of dexmedetomidine (Intraoperative infusion of dexmedetomidine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alpha-2 adrenergic agonist. Area: Anesthesia/Perioperative Medicine.

marketed Alpha-2 adrenergic agonist Alpha-2 adrenergic receptor Anesthesia/Perioperative Medicine Small molecule Live · refreshed every 30 min

Target snapshot

Intraoperative infusion of dexmedetomidine (Intraoperative infusion of dexmedetomidine) — Nanjing First Hospital, Nanjing Medical University. Dexmedetomidine is a selective alpha-2 adrenergic agonist that produces sedation, analgesia, and anxiolysis by activating alpha-2 receptors in the central nervous system.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Intraoperative infusion of dexmedetomidine TARGET	Intraoperative infusion of dexmedetomidine	Nanjing First Hospital, Nanjing Medical University	marketed	Alpha-2 adrenergic agonist	Alpha-2 adrenergic receptor
Randomization of Propofol or Dexmedetomidine	Randomization of Propofol or Dexmedetomidine	Children's Hospital Los Angeles	marketed	Sedative/Hypnotic agents	GABA-A receptor (propofol); Alpha-2 adrenergic receptor (dexmedetomidine)
Clonidine Pill	Clonidine Pill	Weill Medical College of Cornell University	marketed	Alpha-2 adrenergic agonist	Alpha-2 adrenergic receptor
Brimonidine 0.33% gel (Br)	Brimonidine 0.33% gel (Br)	Galderma R&D	marketed	Alpha-2 adrenergic agonist	Alpha-2 adrenergic receptor
Ropivacaine + Dexmedetomidine	Ropivacaine + Dexmedetomidine	Sahiwal medical college sahiwal	marketed	Local anesthetic + alpha-2 adrenergic agonist combination	Voltage-gated sodium channels (ropivacaine); alpha-2 adrenergic receptors (dexmedetomidine)
Fexofenadine HCL and pseudoephedrine HCL	Fexofenadine HCL and pseudoephedrine HCL	Sanofi	marketed	Antihistamine and decongestant combination	H1 receptor (fexofenadine); alpha-1 and alpha-2 adrenergic receptors (pseudoephedrine)
brimonidine topical gel 0.33% & SOC	brimonidine topical gel 0.33% & SOC	Wake Forest University Health Sciences	marketed	Alpha-2 adrenergic agonist	Alpha-2 adrenergic receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Alpha-2 adrenergic agonist class)

USWM, LLC (dba US WorldMeds) · 2 drugs in this class
China International Neuroscience Institution · 1 drug in this class
Icahn School of Medicine at Mount Sinai · 1 drug in this class
Eye Therapies, LLC · 1 drug in this class
Galderma R&D · 1 drug in this class
Guangzhou Women and Children's Medical Center · 1 drug in this class
Derm Research, PLLC · 1 drug in this class
Irmandade da Santa Casa de Misericordia de Sao Paulo · 1 drug in this class
KK Women's and Children's Hospital · 1 drug in this class
American University of Beirut Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Intraoperative infusion of dexmedetomidine — Competitive Intelligence Brief. https://druglandscape.com/ci/intraoperative-infusion-of-dexmedetomidine. Accessed 2026-05-17.

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