Intraoperative anesthetic strategy by Desflurane — Competitive Intelligence Brief

Intraoperative anesthetic strategy by Desflurane (Intraoperative anesthetic strategy by Desflurane) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: General anesthetic. Area: Anesthesiology.

phase 2 General anesthetic GABA_A receptor Anesthesiology Small molecule

Target snapshot

Intraoperative anesthetic strategy by Desflurane (Intraoperative anesthetic strategy by Desflurane) — Assistance Publique - Hôpitaux de Paris. GABA receptor antagonist

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Intraoperative anesthetic strategy by Desflurane TARGET	Intraoperative anesthetic strategy by Desflurane	Assistance Publique - Hôpitaux de Paris	phase 2	General anesthetic	GABA_A receptor
SAGE-547	SAGE-547	Supernus Pharmaceuticals, Inc.	phase 3	antisense oligonucleotide	GABA_A receptor alpha 1 subunit
Sevoflurane + Remifentanyl	Sevoflurane + Remifentanyl	Azienda Ospedaliera San Gerardo di Monza	phase 3	General anesthetic and opioid analgesic	GABA_A receptor and opioid receptors
Sevoflurane, Sufentanil	Sevoflurane, Sufentanil	University of Saskatchewan	phase 3	General anesthetic, Opioid analgesic	GABA_A receptor, Mu-opioid receptor
topiramate, propranolol	topiramate, propranolol	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	phase 3	Anticonvulsant	Voltage-dependent sodium channels, GABA_A receptor
Sevoflurane intravenous anesthesia	Sevoflurane intravenous anesthesia	The Cleveland Clinic	phase 3	Volatile anesthetic	GABA_A receptor
intravenous sedation with propofol	intravenous sedation with propofol	University Hospital, Clermont-Ferrand	phase 3	GABA_A receptor agonist	GABA_A receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (General anesthetic class)

1. Assistance Publique - Hôpitaux de Paris · 1 drug in this class
2. Chung-Ang University Gwangmyeong Hospital · 1 drug in this class
3. Fresenius Kabi · 1 drug in this class
4. Gangnam Severance Hospital · 1 drug in this class
5. Rigshospitalet, Denmark · 1 drug in this class
6. Seoul National University Hospital · 1 drug in this class
7. Universidade Estadual Paulista Júlio de Mesquita Filho · 1 drug in this class
8. University Health Network, Toronto · 1 drug in this class
9. Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · 1 drug in this class