Who are intra-articular botulinum toxin type a's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Magnesium Sulfate, Intradetrusor Botox Injections, Botulinum Toxin A (Botox ), NAFT600 (adult), PrabotulinumtoxinA-Xvfs, NAFT500 (adult).

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Last reviewed 2026-05-18 · How we verify

intra-articular botulinum toxin type a — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

intra-articular botulinum toxin type a (intra-articular botulinum toxin type a) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Botulinum toxin. Area: Rheumatology.

phase 3 Botulinum toxin Acetylcholine release Rheumatology Small molecule Live · refreshed every 30 min

Target snapshot

intra-articular botulinum toxin type a (intra-articular botulinum toxin type a) — Minneapolis Veterans Affairs Medical Center. Intra-articular botulinum toxin type A works by inhibiting the release of acetylcholine, a neurotransmitter that causes muscle contraction.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
intra-articular botulinum toxin type a TARGET	intra-articular botulinum toxin type a	Minneapolis Veterans Affairs Medical Center	phase 3	Botulinum toxin	Acetylcholine release
Magnesium Sulfate	Magnesium Sulfate	Pfizer	marketed	Electrolyte; anticonvulsant	Neuromuscular junction; motor nerve impulse; acetylcholine release	1981-01-01
Intradetrusor Botox Injections	Intradetrusor Botox Injections	The Methodist Hospital Research Institute	marketed	Neurotoxin; botulinum toxin type A	SNARE complex (synaptosomal-associated protein); acetylcholine release machinery
Botulinum Toxin A (Botox )	Botulinum Toxin A (Botox )	Assistance Publique - Hôpitaux de Paris	marketed	Neurotoxin; acetylcholine release inhibitor	SNARE proteins (specifically SNAP-25); acetylcholine release machinery
NAFT600 (adult)	NAFT600 (adult)	Merz North America, Inc.	marketed	Botulinum toxin type A	SNARE complex (acetylcholine release machinery)
PrabotulinumtoxinA-Xvfs	PrabotulinumtoxinA-Xvfs	Lupo Center for Aesthetic and General Dermatology	marketed	Botulinum toxin type A	SNARE complex (acetylcholine release machinery)
NAFT500 (adult)	NAFT500 (adult)	Merz North America, Inc.	marketed	Botulinum toxin type A	SNARE complex (acetylcholine release machinery)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Botulinum toxin class)

Galderma R&D · 2 drugs in this class
Hexsel Dermatology Clinic · 2 drugs in this class
Seoul National University Hospital · 2 drugs in this class
University of Utah · 2 drugs in this class
Daewoong Pharmaceutical Co. LTD. · 2 drugs in this class
EuBiologics Co.,Ltd · 1 drug in this class
Allergan · 1 drug in this class
GlaxoSmithKline · 1 drug in this class
Beth Israel Deaconess Medical Center · 1 drug in this class
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · 1 drug in this class

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Cite this brief

Drug Landscape (2026). intra-articular botulinum toxin type a — Competitive Intelligence Brief. https://druglandscape.com/ci/intra-articular-botulinum-toxin-type-a. Accessed 2026-05-18.

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