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Indomethacin Capsules high dose — Competitive Intelligence Brief
phase 2
NSAID
COX-1 and COX-2
Rheumatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Indomethacin Capsules high dose (Indomethacin Capsules high dose) — Iroko Pharmaceuticals, LLC. Non-selective COX-1 and COX-2 inhibitor
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Indomethacin Capsules high dose TARGET | Indomethacin Capsules high dose | Iroko Pharmaceuticals, LLC | phase 2 | NSAID | COX-1 and COX-2 | |
| Cytotec | Misoprostol | Pfizer | marketed | NSAID combined with prostaglandin analog | Cyclooxygenase (COX-1 and COX-2); Prostaglandin receptors | 1988-01-01 |
| Ropivacaine, Ketorolac and Adrenaline | Ropivacaine, Ketorolac and Adrenaline | University of Aarhus | marketed | Local anesthetic combination with NSAID and vasopressor | Voltage-gated sodium channels (ropivacaine); COX-1 and COX-2 (ketorolac); alpha and beta adrenergic receptors (adrenaline) | |
| Topical diclofenac sodium gel | Topical diclofenac sodium gel | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | marketed | Nonsteroidal anti-inflammatory drug (NSAID) | COX-1 and COX-2 enzymes | |
| Bromfenac Sodium 0.07% | Bromfenac Sodium 0.07% | Retina Research Institute, LLC | marketed | Nonsteroidal anti-inflammatory drug (NSAID) | Cyclooxygenase (COX-1 and COX-2) | |
| ABS | ABS | Teva Branded Pharmaceutical Products R&D, Inc. | marketed | Nonsteroidal anti-inflammatory drug (NSAID) | COX-1 and COX-2 | |
| Ketorolac Nasal Spray | Ketorolac Nasal Spray | Hersh, Elliot V., DMD, MS, PhD | marketed | Nonsteroidal anti-inflammatory drug (NSAID) | Cyclooxygenase (COX-1 and COX-2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NSAID class)
- Antibe Therapeutics Inc. · 3 drugs in this class
- Iroko Pharmaceuticals, LLC · 3 drugs in this class
- Organon and Co · 2 drugs in this class
- Apsen Farmaceutica S.A. · 2 drugs in this class
- Amneal Pharmaceuticals, LLC · 2 drugs in this class
- Behar, Caren, M.D. · 2 drugs in this class
- IDEA AG · 2 drugs in this class
- Noven Pharmaceuticals, Inc. · 2 drugs in this class
- HALEON · 2 drugs in this class
- Pfizer · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Indomethacin Capsules high dose — Competitive Intelligence Brief. https://druglandscape.com/ci/indomethacin-capsules-high-dose. Accessed 2026-05-17.
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