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ABS
Acetylsalicylic acid acts as a non-selective COX inhibitor, reducing inflammation and platelet aggregation.
Acetylsalicylic acid acts as a non-selective COX inhibitor, reducing inflammation and platelet aggregation. Used for Prevention of cardiovascular thrombotic events in patients at risk of such events, reduction of the risk of recurrent ischemic strokes in patients with a history of ischemic stroke or transient ischemic attack, Relief of pain and inflammation in various conditions.
At a glance
| Generic name | ABS |
|---|---|
| Also known as | albuterol sulfate |
| Sponsor | Teva Branded Pharmaceutical Products R&D, Inc. |
| Drug class | Nonsteroidal anti-inflammatory drug (NSAID) |
| Target | COX-1 and COX-2 |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
By inhibiting the COX enzyme, acetylsalicylic acid reduces the production of prostaglandins and thromboxane A2, leading to decreased inflammation and platelet aggregation. This results in its anti-inflammatory and anti-thrombotic effects.
Approved indications
- Prevention of cardiovascular thrombotic events in patients at risk of such events, reduction of the risk of recurrent ischemic strokes in patients with a history of ischemic stroke or transient ischemic attack
- Relief of pain and inflammation in various conditions
Common side effects
- Gastrointestinal upset
- Hypersensitivity reactions
- Renal impairment
Key clinical trials
- A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma (PHASE3)
- A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC) (PHASE1)
- Combined Effects of Dead Bug Exercise and Double Straight Leg Raises Versus Conventional Physical Therapy Exercise on Core Stability and Waist Circumference in Healthy Young Individuals (NA)
- Comparison of a Personalized Maintenance Therapy With the Standard Treatment in Pemphigus (PHASE4)
- The Pause, Learn, and Activate Yourself (PLAY) (NA)
- A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia (PHASE2)
- The Effects of Audio-Based Therapy on Anxiety in Psoriasis (NA)
- Step-Aerobics Versus Core Exercise for Non-HDL Cholesterol Reduction in Sedentary Women (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |