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IcoSema — Competitive Intelligence Brief
phase 3
GLP-1/GIP receptor agonist
GLP-1R, GIPR
Endocrinology
Small molecule
Live · refreshed every 30 min
Target snapshot
IcoSema (IcoSema) — Novo Nordisk A/S. IcoSema is a dual GLP-1/GIP receptor agonist that activates both glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors to improve glycemic control and promote weight loss.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| IcoSema TARGET | IcoSema | Novo Nordisk A/S | phase 3 | GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| Continue GLP/GIP | Continue GLP/GIP | The Cleveland Clinic | marketed | GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| Treatment with tirzapatide | Treatment with tirzapatide | University Medical Centre Ljubljana | marketed | GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| DWJ211 | DWJ211 | Daewoong Pharmaceutical Co. LTD. | phase 3 | Dual GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| LY3537031 | LY3537031 | Eli Lilly and Company | phase 3 | GLP-1/GIP receptor dual agonist | GLP-1R, GIPR | |
| HCP1202 | HCP1202 | Hanmi Pharmaceutical Company Limited | phase 3 | GLP-1/GIP receptor agonist | GLP-1R, GIPR | |
| NNC0487-0111 | NNC0487-0111 | Novo Nordisk A/S | phase 3 | Dual GLP-1/GIP receptor agonist | GLP-1R, GIPR |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GLP-1/GIP receptor agonist class)
- Dong-A ST Co., Ltd. · 2 drugs in this class
- Hanmi Pharmaceutical Company Limited · 1 drug in this class
- Novo Nordisk A/S · 1 drug in this class
- The Cleveland Clinic · 1 drug in this class
- University Medical Centre Ljubljana · 1 drug in this class
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Cite this brief
Drug Landscape (2026). IcoSema — Competitive Intelligence Brief. https://druglandscape.com/ci/icosema. Accessed 2026-05-15.
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