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DWJ211

Daewoong Pharmaceutical Co. LTD. · Phase 3 active Small molecule

DWJ211 is a dual GLP-1/GIP receptor agonist that activates both glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors to improve glycemic control and promote weight loss.

DWJ211 is a dual GLP-1/GIP receptor agonist that activates both glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors to improve glycemic control and promote weight loss. Used for Type 2 diabetes mellitus.

At a glance

Generic nameDWJ211
SponsorDaewoong Pharmaceutical Co. LTD.
Drug classDual GLP-1/GIP receptor agonist
TargetGLP-1R, GIPR
ModalitySmall molecule
Therapeutic areaDiabetes
PhasePhase 3

Mechanism of action

By simultaneously activating GLP-1 and GIP receptors, DWJ211 enhances insulin secretion in response to glucose, slows gastric emptying, and increases satiety signaling in the brain. This dual mechanism produces greater improvements in blood glucose control and body weight reduction compared to single GLP-1 agonists, with a favorable metabolic profile.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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