Last reviewed · How we verify
Hydroquinone 4% Cream — Competitive Intelligence Brief
phase 3
Depigmenting agent
Tyrosinase
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Hydroquinone 4% Cream (Hydroquinone 4% Cream) — Islamabad Medical and Dental College. Hydroquinone inhibits melanin synthesis by suppressing tyrosinase activity, reducing pigment production in the skin.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Hydroquinone 4% Cream TARGET | Hydroquinone 4% Cream | Islamabad Medical and Dental College | phase 3 | Depigmenting agent | Tyrosinase | |
| Hydroquinone Methyl Ether | MEQUINOL | marketed | Skin Lightening Agent | Tyrosinase | 1999-01-01 | |
| Shade Uvaguard | AVOBENZONE | Bayer | marketed | avobenzone | Tyrosinase | 1992-01-01 |
| Infuvite Adult | ASCORBIC ACID | marketed | Vitamin C [EPC] | Tyrosinase | 1985-01-01 | |
| Arbutyne | ARBUTIN | marketed | Adenosine Receptor Agonist [EPC] | Tyrosinase, Polyphenol oxidase 2, Tyrosinase | ||
| Bleaching Agents | Bleaching Agents | André Luis Faria e Silva | marketed | Topical depigmenting agent | Tyrosinase (primary); melanin (direct oxidation) | |
| Tri-luma | Tri-luma | Hexsel Dermatology Clinic | marketed | Topical depigmenting agent combination | Tyrosinase; retinoic acid receptor; glucocorticoid receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Depigmenting agent class)
- Islamabad Medical and Dental College · 1 drug in this class
- National Skin Centre · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Hydroquinone 4% Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/hydroquinone-4-cream. Accessed 2026-05-17.
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