Who are Hyalgan (sodium hyaluronate)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): vitagen plus hyruan, Synvisc-One, injection of hyaluronic acid., Hylan GF-20 alone, Hyaluronic Acid Injection, cross-linked hyaluronic acid.

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Last reviewed 2026-05-16 · How we verify

Hyalgan (sodium hyaluronate) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Hyalgan (sodium hyaluronate) (Hyalgan (sodium hyaluronate)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Viscosupplement. Area: Rheumatology / Orthopedics.

marketed Viscosupplement Synovial fluid replacement (non-receptor mediated) Rheumatology / Orthopedics Small molecule Live · refreshed every 30 min

Target snapshot

Hyalgan (sodium hyaluronate) (Hyalgan (sodium hyaluronate)) — Sanofi. Sodium hyaluronate is a viscoelastic substance that lubricates and cushions joints by mimicking the properties of natural synovial fluid.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Hyalgan (sodium hyaluronate) TARGET	Hyalgan (sodium hyaluronate)	Sanofi	marketed	Viscosupplement	Synovial fluid replacement (non-receptor mediated)
vitagen plus hyruan	vitagen plus hyruan	Taipei Medical University	marketed	Viscosupplement / Joint lubricant	Hyaluronic acid receptor (CD44); joint synovial fluid
Synvisc-One	Synvisc-One	Nature Cell Co. Ltd.	marketed	Viscosupplement; hyaluronic acid derivative	Synovial fluid; joint cartilage surfaces
injection of hyaluronic acid.	injection of hyaluronic acid.	Istituto Ortopedico Rizzoli	marketed	Viscosupplement	Joint synovial fluid (viscoelastic properties)
Hylan GF-20 alone	Hylan GF-20 alone	University of Sao Paulo General Hospital	marketed	Viscosupplement	Hyaluronic acid receptor (CD44)
Hyaluronic Acid Injection	Hyaluronic Acid Injection	Wroclaw Medical University	marketed	Viscosupplement
cross-linked hyaluronic acid	cross-linked hyaluronic acid	Taipei Medical University	marketed	Viscosupplement

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Viscosupplement class)

Istituto Ortopedico Rizzoli · 1 drug in this class
LG Life Sciences · 1 drug in this class
ProChon Biotech Ltd · 1 drug in this class
Sanofi · 1 drug in this class
Taipei Medical University · 1 drug in this class
University of Sao Paulo General Hospital · 1 drug in this class
Wroclaw Medical University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Hyalgan (sodium hyaluronate) — Competitive Intelligence Brief. https://druglandscape.com/ci/hyalgan-sodium-hyaluronate. Accessed 2026-05-16.

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