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HD Vaccine — Competitive Intelligence Brief
marketed
Therapeutic vaccine
Huntingtin protein (HTT)
Neurology
Biologic
Live · refreshed every 30 min
Target snapshot
HD Vaccine (HD Vaccine) — Insight Therapeutics, LLC. HD Vaccine is a therapeutic vaccine designed to stimulate the immune system to target and eliminate cells expressing huntingtin protein, potentially slowing neurodegeneration in Huntington's disease.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| HD Vaccine TARGET | HD Vaccine | Insight Therapeutics, LLC | marketed | Therapeutic vaccine | Huntingtin protein (HTT) | |
| Tat | Tat | Barbara Ensoli, MD | marketed | Therapeutic vaccine | HIV Tat protein | |
| Mycobacterium Vaccae for Injection | Mycobacterium Vaccae for Injection | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | marketed | Immunotherapeutic vaccine | ||
| TEP | TEP | Immungenetics AG | marketed | Therapeutic vaccine | ||
| ASP0113 | ASP0113 | Astellas Pharma Global Development, Inc. | phase 3 | Therapeutic vaccine | CMV antigens (IE-1 and pp65) | |
| ALVAC-HIV vCP1521 + AIDSVAX | ALVAC-HIV vCP1521 + AIDSVAX | U.S. Army Medical Research and Development Command | phase 3 | Therapeutic vaccine | HIV-1 envelope proteins (gp120, gp41) | |
| Hillchol vaccine | Hillchol vaccine | Bharat Biotech International Limited | phase 3 | Therapeutic vaccine |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Therapeutic vaccine class)
- Immunitor LLC · 3 drugs in this class
- GlaxoSmithKline · 2 drugs in this class
- Henogen · 2 drugs in this class
- SK Chemicals Co., Ltd. · 2 drugs in this class
- Merck Sharp & Dohme LLC · 2 drugs in this class
- Cytos Biotechnology AG · 2 drugs in this class
- Clinical Research Organization, Dhaka, Bangladesh · 1 drug in this class
- Barbara Ensoli, MD · 1 drug in this class
- Green Cross Corporation · 1 drug in this class
- Chiang Mai University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). HD Vaccine — Competitive Intelligence Brief. https://druglandscape.com/ci/hd-vaccine. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing