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Gradual dose reduction of semaglutide — Competitive Intelligence Brief

Gradual dose reduction of semaglutide (Gradual dose reduction of semaglutide) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: GLP-1 receptor agonist. Area: Endocrinology / Obesity.

phase 3 GLP-1 receptor agonist GLP-1R Endocrinology / Obesity Small molecule Live · refreshed every 30 min

Target snapshot

Gradual dose reduction of semaglutide (Gradual dose reduction of semaglutide) — Mount Sinai Hospital, Canada. Gradual dose reduction of semaglutide investigates the effects of tapering a GLP-1 receptor agonist to assess weight maintenance, metabolic outcomes, and safety upon discontinuation.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Gradual dose reduction of semaglutide TARGET Gradual dose reduction of semaglutide Mount Sinai Hospital, Canada phase 3 GLP-1 receptor agonist GLP-1R
semaglutide combined with metformin semaglutide combined with metformin The First Affiliated Hospital of Xiamen University marketed GLP-1 receptor agonist combined with biguanide GLP-1R; AMPK pathway
Semaglutide Pen Injector Semaglutide Pen Injector University of Pennsylvania marketed GLP-1 receptor agonist GLP-1R
Semaglutide Pen Injector [Ozempic] Semaglutide Pen Injector [Ozempic] University of Nottingham marketed GLP-1 receptor agonist GLP-1R
Semaglutide Injectable Product Semaglutide Injectable Product Neurogastrx, Inc. marketed GLP-1 receptor agonist GLP-1R
Dulaglutide Pen Dulaglutide Pen Eli Lilly and Company marketed GLP-1 receptor agonist GLP-1R
Semaglutide (Rybelsus®) Semaglutide (Rybelsus®) Instituto Mexicano del Seguro Social marketed GLP-1 receptor agonist GLP-1R (GLP-1 receptor)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (GLP-1 receptor agonist class)

  1. Hanmi Pharmaceutical Company Limited · 30 drugs in this class
  2. Eli Lilly and Company · 8 drugs in this class
  3. Novo Nordisk A/S · 6 drugs in this class
  4. GlaxoSmithKline · 6 drugs in this class
  5. Sanofi · 4 drugs in this class
  6. AstraZeneca · 4 drugs in this class
  7. Daewoong Pharmaceutical Co. LTD. · 4 drugs in this class
  8. Hangzhou Sciwind Biosciences Co., Ltd. · 3 drugs in this class
  9. Jiangsu Hansoh Pharmaceutical Co., Ltd. · 2 drugs in this class
  10. Huons Co., Ltd. · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). Gradual dose reduction of semaglutide — Competitive Intelligence Brief. https://druglandscape.com/ci/gradual-dose-reduction-of-semaglutide. Accessed 2026-05-18.

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