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Nitroglycerin — Competitive Intelligence Brief
marketed
Nitrate Vasodilator [EPC]
guanylate cyclase
Metabolic
Small molecule
Live · refreshed every 30 min
Target snapshot
Nitroglycerin (glyceryl trinitrate) — Fougera. Nitroglycerin forms nitric oxide, activating guanylate cyclase and increasing cyclic GMP, leading to smooth muscle relaxation and vasodilation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Nitroglycerin TARGET | glyceryl trinitrate | Fougera | marketed | Nitrate Vasodilator [EPC] | guanylate cyclase | 1981-01-01 |
| Verquvo | VERICIGUAT | Merck & Co. | marketed | Soluble Guanylate Cyclase Stimulator [EPC] | Guanylate cyclase soluble subunit beta-1 | 2021-01-01 |
| Adempas | RIOCIGUAT | Bayer | marketed | Soluble Guanylate Cyclase Stimulator [EPC] | Guanylate cyclase soluble subunit beta-1 | 2013-01-01 |
| Inomax | NITRIC OXIDE | Vero Biotech Inc | marketed | Standardized Chemical Allergen [EPC] | Soluble guanylate cyclase | 1999-01-01 |
| Nitroglycerin (NTG) | Nitroglycerin (NTG) | Bristol-Myers Squibb | marketed | Nitrate vasodilator | Soluble guanylate cyclase (via nitric oxide) | |
| Glyceryl trinitrate 0.2 | Glyceryl trinitrate 0.2 | Recep Tayyip Erdogan University | marketed | Nitrate vasodilator | Soluble guanylate cyclase (via nitric oxide) | |
| nitric oxide gel | nitric oxide gel | China Medical University Hospital | marketed | Topical vasodilator | Soluble guanylate cyclase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Nitroglycerin · 7872049 · US
- — Nitroglycerin · 9101592 · US
Sponsor landscape (Nitrate Vasodilator [EPC] class)
- · 2 drugs in this class
- Centre for Addiction and Mental Health · 1 drug in this class
- Fougera · 1 drug in this class
- Novartis · 1 drug in this class
- Stefan Fischli · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Nitroglycerin — Competitive Intelligence Brief. https://druglandscape.com/ci/glyceryl-trinitrate. Accessed 2026-05-13.
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