Who are Generic acyclovir's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lonsurf, Dendrid, Peginterferon alfa-2a + ribavirin, Valacyclovir (ZELITREX), VAL, Acyclovir (ACV).

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Generic acyclovir — Competitive Intelligence Brief

Generic acyclovir (Generic acyclovir) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Nucleoside analog antiviral. Area: Infectious Disease / Virology.

phase 3 Nucleoside analog antiviral Viral DNA polymerase (HSV and VZV) Infectious Disease / Virology Small molecule Live · refreshed every 30 min

Target snapshot

Generic acyclovir (Generic acyclovir) — University of Washington. Acyclovir inhibits viral DNA polymerase to prevent replication of herpes simplex virus and varicella-zoster virus.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Generic acyclovir TARGET	Generic acyclovir	University of Washington	phase 3	Nucleoside analog antiviral	Viral DNA polymerase (HSV and VZV)
Lonsurf	TIPIRACIL	Taiho Oncology Inc	marketed	Nucleoside Analog Antiviral [EPC]	Thymidine phosphorylase	2015-01-01
Dendrid	IDOXURIDINE	Novartis	marketed	Nucleoside Analog Antiviral	Thymidine kinase, cytosolic	1963-01-01
Peginterferon alfa-2a + ribavirin	Peginterferon alfa-2a + ribavirin	Hospital Clinico Universitario San Cecilio	marketed	Interferon alpha + nucleoside analog antiviral combination	Interferon-alpha receptor (IFNAR); HCV RNA-dependent RNA polymerase
Valacyclovir (ZELITREX)	Valacyclovir (ZELITREX)	Assistance Publique - Hôpitaux de Paris	marketed	Nucleoside analog antiviral	Viral DNA polymerase (herpesvirus)
VAL	VAL	Estetra	marketed	Nucleoside analog antiviral	Cytomegalovirus (CMV) DNA polymerase
Acyclovir (ACV)	Acyclovir (ACV)	French National Agency for Research on AIDS and Viral Hepatitis	marketed	Nucleoside analog antiviral	Viral DNA polymerase (herpes simplex virus and varicella-zoster virus)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2029-09-22 — Lonsurf · RE46284 · US
2034-06-17 — Lonsurf · 10457666 · US
2034-06-17 — Lonsurf · 9527833 · US
2034-09-05 — Lonsurf · 9943537 · US
2037-02-03 — Lonsurf · 10456399 · US
2037-02-03 — Lonsurf · 10960004 · US

Sponsor landscape (Nucleoside analog antiviral class)

Merck Sharp & Dohme LLC · 3 drugs in this class
Hoffmann-La Roche · 2 drugs in this class
Göteborg University · 2 drugs in this class
Estetra · 1 drug in this class
Padagis LLC · 1 drug in this class
MinaPharm Pharmaceuticals · 1 drug in this class
French National Agency for Research on AIDS and Viral Hepatitis · 1 drug in this class
NYU Langone Health · 1 drug in this class
Assistance Publique - Hôpitaux de Paris · 1 drug in this class
Ain Shams University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Generic acyclovir — Competitive Intelligence Brief. https://druglandscape.com/ci/generic-acyclovir. Accessed 2026-05-14.

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