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Estriol Cream 0.1% — Competitive Intelligence Brief

Estriol Cream 0.1% (Estriol Cream 0.1%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Estrogen receptor agonist. Area: Gynecology / Menopause.

marketed Estrogen receptor agonist Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) Gynecology / Menopause Small molecule Live · refreshed every 30 min

Target snapshot

Estriol Cream 0.1% (Estriol Cream 0.1%) — Dr. August Wolff GmbH & Co. KG Arzneimittel. Estriol is a weak estrogen that binds to estrogen receptors in vaginal and urogenital tissues to restore epithelial maturation and improve local tissue health.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Estriol Cream 0.1% TARGET Estriol Cream 0.1% Dr. August Wolff GmbH & Co. KG Arzneimittel marketed Estrogen receptor agonist Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)
estriol cream estriol cream Hatice Tukenmez Kurnaz marketed Estrogen receptor agonist Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)
Vaginal estradiol tablets Vaginal estradiol tablets Johns Hopkins University marketed Estrogen receptor agonist Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)
estradiol valerat estradiol valerat farzaneh hojjat marketed Estrogen receptor agonist Estrogen receptor alpha (ERα), Estrogen receptor beta (ERβ)
Estradiol 0.01% Vag Cream Estradiol 0.01% Vag Cream TriHealth Inc. marketed Estrogen receptor agonist Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)
Estradiol (E2) Estradiol (E2) Martin Blomberg Jensen phase 3 Estrogen receptor agonist Estrogen receptor alpha (ERα), Estrogen receptor beta (ERβ)
Generic Estradiol Vaginal Cream USP, 0.01% Generic Estradiol Vaginal Cream USP, 0.01% Actavis Inc. phase 3 Estrogen receptor agonist Estrogen receptor alpha (ERα), Estrogen receptor beta (ERβ)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Estrogen receptor agonist class)

  1. Actavis Inc. · 1 drug in this class
  2. Bayer · 1 drug in this class
  3. Dr. August Wolff GmbH & Co. KG Arzneimittel · 1 drug in this class
  4. Hatice Tukenmez Kurnaz · 1 drug in this class
  5. Johns Hopkins University · 1 drug in this class
  6. Martin Blomberg Jensen · 1 drug in this class
  7. TriHealth Inc. · 1 drug in this class
  8. farzaneh hojjat · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Estriol Cream 0.1% — Competitive Intelligence Brief. https://druglandscape.com/ci/estriol-cream-0-1. Accessed 2026-05-16.

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