Who are Epinephrine HFA-MDI (E004)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): ephedrine and phenylephrine, Norepinephrine intra-arteriel/hepatic, nebulized epinephrine, Epinephrine concentration of 1:1000000.

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Last reviewed 2026-06-10 · How we verify

Epinephrine HFA-MDI (E004) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Epinephrine HFA-MDI (E004) (Epinephrine HFA-MDI (E004)) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Sympathomimetic amine / Adrenergic agonist. Area: Pulmonary / Emergency Medicine.

phase 3 Sympathomimetic amine / Adrenergic agonist Alpha-1 adrenergic receptor, Beta-2 adrenergic receptor Pulmonary / Emergency Medicine Small molecule Live · refreshed every 30 min

Target snapshot

Epinephrine HFA-MDI (E004) (Epinephrine HFA-MDI (E004)) — Amphastar Pharmaceuticals, Inc.. Epinephrine is a sympathomimetic amine that binds to alpha and beta adrenergic receptors to produce rapid bronchodilation, increased heart rate, and vasoconstriction.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Epinephrine HFA-MDI (E004) TARGET	Epinephrine HFA-MDI (E004)	Amphastar Pharmaceuticals, Inc.	phase 3	Sympathomimetic amine / Adrenergic agonist	Alpha-1 adrenergic receptor, Beta-2 adrenergic receptor
ephedrine and phenylephrine	ephedrine and phenylephrine	University Hospital, Clermont-Ferrand	marketed	Sympathomimetic amine / Adrenergic agonist	Alpha-1 adrenergic receptor, beta-1 adrenergic receptor, beta-2 adrenergic receptor
Norepinephrine intra-arteriel/hepatic	Norepinephrine intra-arteriel/hepatic	University Health Network, Toronto	marketed	Sympathomimetic amine / Adrenergic agonist	Alpha-1 adrenergic receptor, Beta-1 adrenergic receptor
nebulized epinephrine	nebulized epinephrine	Oman Medical Speciality Board	marketed	Sympathomimetic amine / Adrenergic agonist	Alpha-1 and beta-2 adrenergic receptors
Epinephrine concentration of 1:1000000	Epinephrine concentration of 1:1000000	Al-Azhar University	phase 3	Sympathomimetic amine / Adrenergic agonist	Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Sympathomimetic amine / Adrenergic agonist class)

Al-Azhar University · 1 drug in this class
Amphastar Pharmaceuticals, Inc. · 1 drug in this class
Oman Medical Speciality Board · 1 drug in this class
University Health Network, Toronto · 1 drug in this class
University Hospital, Clermont-Ferrand · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Epinephrine HFA-MDI (E004) — Competitive Intelligence Brief. https://druglandscape.com/ci/epinephrine-hfa-mdi-e004. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing