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DXM + Propofol — Competitive Intelligence Brief

DXM + Propofol (DXM + Propofol) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Dissociative anesthetic combination. Area: Anesthesia.

marketed Dissociative anesthetic combination NMDA receptor (DXM); GABA-A receptor (propofol) Anesthesia Small molecule Live · refreshed every 30 min

Target snapshot

DXM + Propofol (DXM + Propofol) — Seoul National University Hospital. DXM (dextromethorphan) and propofol together provide dissociative anesthesia and analgesia through NMDA receptor antagonism and GABAergic potentiation.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
DXM + Propofol TARGET DXM + Propofol Seoul National University Hospital marketed Dissociative anesthetic combination NMDA receptor (DXM); GABA-A receptor (propofol)
Midazolam+Ketamine Combination Midazolam+Ketamine Combination Universidad de Cartagena marketed Sedative-hypnotic and dissociative anesthetic combination GABA-A receptor (midazolam); NMDA receptor (ketamine)
Haloperidol + Ketamine Haloperidol + Ketamine University Hospital, Basel, Switzerland marketed Antipsychotic + Dissociative anesthetic combination Dopamine D2 receptor (haloperidol); NMDA glutamate receptor (ketamine)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Dissociative anesthetic combination class)

  1. Seoul National University Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). DXM + Propofol — Competitive Intelligence Brief. https://druglandscape.com/ci/dxm-propofol. Accessed 2026-05-14.

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