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Doxazosin extended release — Competitive Intelligence Brief
marketed
Alpha-1 adrenergic receptor antagonist
Alpha-1 adrenergic receptor
Cardiovascular, Urology
Small molecule
Live · refreshed every 30 min
Target snapshot
Doxazosin extended release (Doxazosin extended release) — University of Arkansas. Doxazosin is an alpha-1 adrenergic receptor antagonist that relaxes smooth muscle in the prostate and bladder neck to improve urinary flow, and also dilates blood vessels to lower blood pressure.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Doxazosin extended release TARGET | Doxazosin extended release | University of Arkansas | marketed | Alpha-1 adrenergic receptor antagonist | Alpha-1 adrenergic receptor | |
| RASi plus carvedilol | RASi plus carvedilol | Federal University of Minas Gerais | marketed | ACE inhibitor or ARB combined with non-selective beta-blocker | Angiotensin II receptor / ACE enzyme; beta-1 and beta-2 adrenergic receptors; alpha-1 adrenergic receptor | |
| Phenylephrine bolus 50 micrograms | Phenylephrine bolus 50 micrograms | Rawalpindi Medical College | marketed | Alpha-1 adrenergic agonist | Alpha-1 adrenergic receptor | |
| Midodrine + pyridostigmine | Midodrine + pyridostigmine | Seoul National University Hospital | marketed | Alpha-1 adrenergic agonist + acetylcholinesterase inhibitor combination | Alpha-1 adrenergic receptor; acetylcholinesterase | |
| Bupivacaine-adrenaline | Bupivacaine-adrenaline | University of Aarhus | marketed | Local anesthetic with vasopressor | Voltage-gated sodium channels; alpha-1 adrenergic receptors (adrenaline component) | |
| Bolus Phenylephrine/Ephedrine Treatment | Bolus Phenylephrine/Ephedrine Treatment | IWK Health Centre | marketed | Sympathomimetic amines / Vasopressors | Alpha-1 adrenergic receptor (phenylephrine); Alpha and beta adrenergic receptors (ephedrine) | |
| Pseudoephedrine/Paracetamol | Pseudoephedrine/Paracetamol | McNeil AB | marketed | Decongestant/analgesic combination | Alpha-1 adrenergic receptor (pseudoephedrine); COX inhibition (paracetamol) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Alpha-1 adrenergic receptor antagonist class)
- Brian J Lipworth · 1 drug in this class
- CHU de Quebec-Universite Laval · 1 drug in this class
- Eli Lilly and Company · 1 drug in this class
- Haffkine Bio-Pharmaceutical Corporation Ltd. · 1 drug in this class
- Hospital Authority, Hong Kong · 1 drug in this class
- Japan Heart Foundation · 1 drug in this class
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · 1 drug in this class
- San Francisco Veterans Affairs Medical Center · 1 drug in this class
- Sanofi · 1 drug in this class
- Shanghai Huilun Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Doxazosin extended release — Competitive Intelligence Brief. https://druglandscape.com/ci/doxazosin-extended-release. Accessed 2026-05-16.
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