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Last reviewed 2026-06-10 · How we verify

Vaso-occlusive crisis in sickle cell disease — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Vaso-occlusive crisis in sickle cell disease (disease) competitive landscape: 2 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

2 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Vaso-occlusive crisis in sickle cell disease, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	Line of therapy	First approval
Selg1	CRIZANLIZUMAB	Novartis	Selectin Blocker [EPC]	P-selectin		2019-01-01
ADAKVEO	CRIZANLIZUMAB-TMCA	NOVARTIS PHARMS CORP	Selectin Blocker [EPC]	P-selectin

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

NOVARTIS PHARMS CORP · 1 drug in Vaso-occlusive crisis in sickle cell disease
Novartis · 1 drug in Vaso-occlusive crisis in sickle cell disease

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Every new regulatory action, PDUFA date, or trial completion in Vaso-occlusive crisis in sickle cell disease:

Cite this brief

Drug Landscape (2026). Vaso-occlusive crisis in sickle cell disease — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/vaso-occlusive-crisis-in-sickle-cell-disease. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing