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Last reviewed 2026-06-10 · How we verify

Treatment-Resistant Schizophrenia — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Treatment-Resistant Schizophrenia (disease) competitive landscape: 3 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

3 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Treatment-Resistant Schizophrenia, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Clozaril	CLOZAPINE	Jazz Pharmaceuticals	Atypical Antipsychotic [EPC]	D2, 5-HT2A	1989-01-01
Fazaclo	Fazaclo	Manhattan Psychiatric Center		Aldehyde oxidase, UDP-glucuronosyltransferase 1-4, 5-hydroxytryptamine receptor 1E
Clozaril	Clozaril	Dong Wha Pharmaceutical Co. Ltd.		Aldehyde oxidase, UDP-glucuronosyltransferase 1-4, 5-hydroxytryptamine receptor 1E

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Dong Wha Pharmaceutical Co. Ltd. · 1 drug in Treatment-Resistant Schizophrenia
Jazz Pharmaceuticals · 1 drug in Treatment-Resistant Schizophrenia
Manhattan Psychiatric Center · 1 drug in Treatment-Resistant Schizophrenia

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Every new regulatory action, PDUFA date, or trial completion in Treatment-Resistant Schizophrenia:

Cite this brief

Drug Landscape (2026). Treatment-Resistant Schizophrenia — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/treatment-resistant-schizophrenia. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing