Last reviewed · How we verify
Fazaclo
At a glance
| Generic name | Fazaclo |
|---|---|
| Also known as | Fazaclo clozapine |
| Sponsor | Manhattan Psychiatric Center |
| Target | Aldehyde oxidase, UDP-glucuronosyltransferase 1-4, 5-hydroxytryptamine receptor 1E |
| Modality | Small molecule |
| Therapeutic area | Neuroscience |
| Phase | FDA-approved |
Approved indications
- Suicidal Behavior in Schizoaffective Disorder
- Suicidal Behavior in Schizophrenia
- Treatment-Resistant Schizophrenia
Common side effects
- Tachycardia
- Sedation
- Constipation
- Dizziness
- Hypotension
- Fever
- Hypersalivation
- Sweating
- Dry Mouth
- Visual Disturbances
- Nausea
- Salivary hypersecretion
Key clinical trials
- An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine (PHASE4)
- The Combination of Pharmacotherapy and Cognitive Behavioral Psychotherapy Under the Recovery Perspective. (PHASE1)
- CLOZAPINE Response in Biotype-1 (PHASE4)
- Τhe Combination of Pharmacotherapy With RECOVERYTRSGR and RECOVERYTRSBDGR. (PHASE4)
- Maintenance ElectroConvulsive Therapy in Clozapine RESISTant Schizophrenia - the MECT-RESIST Trial (NA)
- Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial (PHASE4)
- A Study of the Safety and Tolerability of GA in the Treatment of Patients With Refractory Neuropathic Pain (EARLY_PHASE1)
- Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Fazaclo CI brief — competitive landscape report
- Fazaclo updates RSS · CI watch RSS
- Manhattan Psychiatric Center portfolio CI