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Tension-type headache — Treatment Landscape & Competitive Intelligence

Tension-type headache (disease) competitive landscape: 4 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

4 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Tension-type headache, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Butalbital, Aspirin And Caffeine BUTALBITAL Actavis Labs Ut Inc Barbiturate [EPC] GABA-A receptor alpha-1/beta-3/gamma-2 1976-01-01
Acetaminophen Paracetamol Polymedica acetaminophen Transient receptor potential cation channel subfamily V member 4 1968-01-01
Codeine codeine phosphate Generic (multiple manufacturers) Opioid analgesic, Antitussive Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor 1950-01-01
Norgesic caffeine Hikma Central Nervous System Stimulant [EPC] Adenosine receptor A2a 1948-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Actavis Labs Ut Inc · 1 drug in Tension-type headache
  2. Generic (multiple manufacturers) · 1 drug in Tension-type headache
  3. Hikma · 1 drug in Tension-type headache
  4. Polymedica · 1 drug in Tension-type headache

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Every new regulatory action, PDUFA date, or trial completion in Tension-type headache:

Cite this brief

Drug Landscape (2026). Tension-type headache — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/tension-type-headache. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing