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Tension-type headache — Treatment Landscape & Competitive Intelligence
4 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Butalbital, Aspirin And Caffeine | BUTALBITAL | Actavis Labs Ut Inc | Barbiturate [EPC] | GABA-A receptor alpha-1/beta-3/gamma-2 | 1976-01-01 | |
| Acetaminophen | Paracetamol | Polymedica | acetaminophen | Transient receptor potential cation channel subfamily V member 4 | 1968-01-01 | |
| Codeine | codeine phosphate | Generic (multiple manufacturers) | Opioid analgesic, Antitussive | Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor | 1950-01-01 | |
| Norgesic | caffeine | Hikma | Central Nervous System Stimulant [EPC] | Adenosine receptor A2a | 1948-01-01 |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- Actavis Labs Ut Inc · 1 drug in Tension-type headache
- Generic (multiple manufacturers) · 1 drug in Tension-type headache
- Hikma · 1 drug in Tension-type headache
- Polymedica · 1 drug in Tension-type headache
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Cite this brief
Drug Landscape (2026). Tension-type headache — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/tension-type-headache. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing