How many drugs treat Primary ovarian failure?

Drug Landscape tracks 5 marketed treatments for Primary ovarian failure (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

What's the most recent regulatory action in Primary ovarian failure?

Most recent: Estring — FDA approved.

How do I subscribe to ongoing alerts?

Subscribe to /feed/disease/primary-ovarian-failure.xml in Feedly / Inoreader. Every regulatory action, PDUFA date, or trial completion in this treatment area lands in your feed automatically.

Last reviewed 2026-06-10 · How we verify

Primary ovarian failure — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Primary ovarian failure (disease) competitive landscape: 5 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

5 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Primary ovarian failure, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Depoestradiol	ESTRADIOL CYPIONATE	Pfizer	Estrogen	Estrogen receptor beta	1979-01-01
Estrace	ESTRADIOL	Pfizer	Estrogen	Estrogen receptor	1975-01-01
Micronor	norethisterone	Johnson & Johnson	Progestin	GnRH receptors	1962-01-01
Delestrogen	ESTRADIOL VALERATE	Ph Health	Estrogen	Estrogen receptor	1954-01-01
Menest	Estrogens, Esterified	Pfizer Inc.	Estrogen	Estrogen receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

2026-05-11 — Estring · FDA · approved · US

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Pfizer · 2 drugs in Primary ovarian failure
Pfizer Inc. · 2 drugs in Primary ovarian failure
Johnson & Johnson · 1 drug in Primary ovarian failure
Ph Health · 1 drug in Primary ovarian failure

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Every new regulatory action, PDUFA date, or trial completion in Primary ovarian failure:

Cite this brief

Drug Landscape (2026). Primary ovarian failure — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/primary-ovarian-failure. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing