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Pain — Treatment Landscape & Competitive Intelligence

Pain (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Pain, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Nucynta TAPENTADOL Collegium Pharm Inc Opioid Agonist Mu-type opioid receptor 2008-01-01
Xibrom BROMFENAC Bausch Health Nonsteroidal Anti-inflammatory Drug Prostaglandin G/H synthase 2 2005-01-01
Lodine ETODOLAC Pfizer Nonsteroidal Anti-inflammatory Drug [EPC] Prostaglandin G/H synthase 2 1991-01-01
Dalgan DEZOCINE AstraZeneca dezocine Mu-type opioid receptor 1989-01-01
Voltaren DICLOFENAC Hisamitsu Pharmaceutical Co., Inc Nonsteroidal Anti-inflammatory Drug Prostaglandin G/H synthase 2 1988-01-01
Arthrotec Diclofenac Sodium Pfizer diclofenac Acid-sensing ion channel 3 1988-01-01
Dilaudid-Hp Hydromorphone Hydrochloride Fresenius Kabi Opioid agonist Mu-opioid receptor 1984-01-01
Dilaudid-Hp HYDROMORPHONE Fresenius Kabi Opioid Agonist mu-opioid receptor 1984-01-01
Renacidin CITRIC ACID Baxter Anti-coagulant 1982-01-01
Aleve naproxen Generic (originally Syntex) NSAID Aldo-keto reductase family 1 member C2, Aldo-keto reductase family 1 member C3, Prostaglandin G/H synthase 1 1976-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. · 22 drugs in Pain
  2. Pfizer · 4 drugs in Pain
  3. Generic (multiple manufacturers) · 3 drugs in Pain
  4. Endo · 2 drugs in Pain
  5. Fresenius Kabi · 2 drugs in Pain
  6. Bausch Health · 2 drugs in Pain
  7. Bp Consulting, Inc · 1 drug in Pain
  8. Baxter · 1 drug in Pain
  9. Ain Shams University · 1 drug in Pain
  10. Energique, Inc. · 1 drug in Pain
  11. Collegium Pharm Inc · 1 drug in Pain
  12. Caraco · 1 drug in Pain

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Cite this brief

Drug Landscape (2026). Pain — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/pain. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing