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Microsatellite instability-high colorectal cancer — Treatment Landscape & Competitive Intelligence

Microsatellite instability-high colorectal cancer (disease) competitive landscape: 4 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

4 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Microsatellite instability-high colorectal cancer, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Opdivo nivolumab Bristol-Myers Squibb Programmed Death Receptor-1 Blocking Antibody [EPC] Programmed cell death protein 1 2014-01-01
Pembrolizuma Pembrolizuma Memorial Sloan Kettering Cancer Center Programmed cell death protein 1
Yervoy Yervoy Bristol-Myers Squibb Cytotoxic T-lymphocyte protein 4
Yervoy ipilimumab Bristol-Myers Squibb CTLA-4-directed Blocking Antibody Cytotoxic T-lymphocyte protein 4 2011-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Bristol-Myers Squibb · 3 drugs in Microsatellite instability-high colorectal cancer
  2. Memorial Sloan Kettering Cancer Center · 1 drug in Microsatellite instability-high colorectal cancer

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Every new regulatory action, PDUFA date, or trial completion in Microsatellite instability-high colorectal cancer:

Cite this brief

Drug Landscape (2026). Microsatellite instability-high colorectal cancer — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/microsatellite-instability-high-colorectal-cancer. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing