How many drugs treat Methotrexate Toxicity?

Drug Landscape tracks 3 marketed treatments for Methotrexate Toxicity (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

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Last reviewed 2026-06-10 · How we verify

Methotrexate Toxicity — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Methotrexate Toxicity (disease) competitive landscape: 3 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

3 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Methotrexate Toxicity, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Fusilev	Levofolinic acid	Spectrum Pharms	Folate Analog		2008-01-01
Fusilev	levoleucovorin	Acrotech Biopharma	Folate Analog		2008-01-01
Wellcovorin	leucovorin	Pfizer Japan Inc	Folate Analog	Dihydrofolate reductase	1952-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Acrotech Biopharma · 1 drug in Methotrexate Toxicity
Pfizer Japan Inc · 1 drug in Methotrexate Toxicity
Spectrum Pharms · 1 drug in Methotrexate Toxicity

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Every new regulatory action, PDUFA date, or trial completion in Methotrexate Toxicity:

Cite this brief

Drug Landscape (2026). Methotrexate Toxicity — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/methotrexate-toxicity. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing