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Medullary thyroid carcinoma — Treatment Landscape & Competitive Intelligence

Medullary thyroid carcinoma (disease) competitive landscape: 7 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

7 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Medullary thyroid carcinoma, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Retevmo SELPERCATINIB Eli Lilly Kinase Inhibitor [EPC] Proto-oncogene tyrosine-protein kinase receptor Ret 2020-01-01
Gavreto PRALSETINIB Rigel Pharms Kinase Inhibitor [EPC] RET 2020-01-01
Cometriq Cabometyx Exelixis Kinase Inhibitor Vascular endothelial growth factor receptor 2 2012-01-01
Cometriq CABOZANTINIB Exelixis Inc Kinase Inhibitor Vascular endothelial growth factor receptor 2 2012-01-01
Caprelsa VANDETANIB Sanofi Kinase Inhibitor [EPC] Receptor-interacting serine/threonine-protein kinase 2 2011-01-01
Caprelsa Caprelsa Genzyme, a Sanofi Company AarF domain-containing protein kinase 4, Bone morphogenetic protein receptor type-1B, Chaperone activity of bc1 complex-like, mitochondrial
Zactima Zactima Barbara Ann Karmanos Cancer Institute AarF domain-containing protein kinase 4, Bone morphogenetic protein receptor type-1B, Chaperone activity of bc1 complex-like, mitochondrial

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Barbara Ann Karmanos Cancer Institute · 1 drug in Medullary thyroid carcinoma
  2. Eli Lilly · 1 drug in Medullary thyroid carcinoma
  3. Exelixis · 1 drug in Medullary thyroid carcinoma
  4. Exelixis Inc · 1 drug in Medullary thyroid carcinoma
  5. Genzyme, a Sanofi Company · 1 drug in Medullary thyroid carcinoma
  6. Rigel Pharms · 1 drug in Medullary thyroid carcinoma
  7. Sanofi · 1 drug in Medullary thyroid carcinoma

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Cite this brief

Drug Landscape (2026). Medullary thyroid carcinoma — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/medullary-thyroid-carcinoma. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing