How many drugs treat Klinefelter's syndrome, XXY?

Drug Landscape tracks 5 marketed treatments for Klinefelter's syndrome, XXY (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

How do I subscribe to ongoing alerts?

Subscribe to /feed/disease/klinefelter-s-syndrome-xxy.xml in Feedly / Inoreader. Every regulatory action, PDUFA date, or trial completion in this treatment area lands in your feed automatically.

Last reviewed 2026-06-10 · How we verify

Klinefelter's syndrome, XXY — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Klinefelter's syndrome, XXY (disease) competitive landscape: 5 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

5 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Klinefelter's syndrome, XXY, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Testosterone Cypionate	Testosterone Cypionate	Azurity	Androgen	Androgen receptor	1978-01-01
Androgel	TESTOSTERONE	Besins Hlthcare	Androgen [EPC]	Androgen receptor	1972-01-01
Xyosted (Autoinjector)	testosterone enantate	Endo	Androgen	Androgen receptor	1953-01-01
Testosteron	Testosteron	Gulhane School of Medicine		Corticosteroid-binding globulin, Alpha-synuclein, Lanosterol 14-alpha demethylase
Testosterone cypionate (200mg/3ml)	Testosterone cypionate (200mg/3ml)	Leticia Maria Defendi Barboza Marson	Androgenic steroid	Androgen receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

· 2 drugs in Klinefelter's syndrome, XXY
Azurity · 1 drug in Klinefelter's syndrome, XXY
Besins Hlthcare · 1 drug in Klinefelter's syndrome, XXY
Endo · 1 drug in Klinefelter's syndrome, XXY
Gulhane School of Medicine · 1 drug in Klinefelter's syndrome, XXY
Leticia Maria Defendi Barboza Marson · 1 drug in Klinefelter's syndrome, XXY

Subscribe to ongoing alerts

Every new regulatory action, PDUFA date, or trial completion in Klinefelter's syndrome, XXY:

Cite this brief

Drug Landscape (2026). Klinefelter's syndrome, XXY — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/klinefelter-s-syndrome-xxy. Accessed 2026-06-10.

Klinefelter's syndrome, XXY full disease profile — treatment pathway, diagnostics, guidelines
Browse all CI briefs
Build a custom feed

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing