Last reviewed 2026-04-20 · How we verify

Testosteron

At a glance

Approved indications

• Bilateral Anorchia
• Bilateral orchidectomy
• Chemotherapy-Induced Hypogonadism
• Deficiency of testosterone biosynthesis
• Delayed puberty
• Hormone receptor positive malignant neoplasm of breast
• Hypogonadotropic hypogonadism
• Hypopituitarism
• Inhibition of lactation procedure
• Klinefelter's syndrome, XXY
• LHRH Deficiency
• Male hypogonadism
• Menopausal flushing
• Primary Hypogonadism due to Bilateral Torsion
• Primary Hypogonadism due to Orchitis
• Undescended testicle

Common side effects

• PSA increased
• Emotional lability
• Contact dermatitis
• Frequent urination
• Hyperlipidemia
• Sinusitis
• Increased hemoglobin or hematocrit
• Hypertension
• Acne
• Libido decreased
• Insomnia
• Benign prostatic hyperplasia

Key clinical trials

• Body Composition Assessment in Transgender Population.
• Novel Approaches for Minimizing Drug-Induced QT Interval Lengthening (PHASE4)
• Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism (PHASE2)
• Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC (PHASE2)
• Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response (PHASE2)
• Does Human Skeletal Muscle Possess an Epigenetic Memory of Testosterone? (PHASE2, PHASE3)
• Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance (PHASE4)
• Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer (PHASE1)

Primary sources

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